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SARS-CoV-2 evades immune detection in alveolar macrophages.
Dalskov L, Møhlenberg M, Thyrsted J, Blay-Cadanet J, Poulsen ET, Folkersen BH, Skaarup SH, Olagnier D, Reinert L, Enghild JJ, Hoffmann HJ, Holm CK, Hartmann R. Dalskov L, et al. Among authors: hartmann r. EMBO Rep. 2020 Dec 3;21(12):e51252. doi: 10.15252/embr.202051252. Epub 2020 Oct 28. EMBO Rep. 2020. PMID: 33112036 Free PMC article.
Functional IRF3 deficiency in a patient with herpes simplex encephalitis.
Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH. Andersen LL, et al. Among authors: hartmann r. J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27. J Exp Med. 2015. PMID: 26216125 Free PMC article.
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.
Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, Hornung V, Lebbink RJ, Duch M, Fitzgerald KA, Bahrami S, Mikkelsen JG, Hartmann R, Paludan SR. Holm CK, et al. Among authors: hartmann r. Nat Commun. 2016 Feb 19;7:10680. doi: 10.1038/ncomms10680. Nat Commun. 2016. PMID: 26893169 Free PMC article.
HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression.
Christensen MH, Jensen SB, Miettinen JJ, Luecke S, Prabakaran T, Reinert LS, Mettenleiter T, Chen ZJ, Knipe DM, Sandri-Goldin RM, Enquist LW, Hartmann R, Mogensen TH, Rice SA, Nyman TA, Matikainen S, Paludan SR. Christensen MH, et al. Among authors: hartmann r. EMBO J. 2016 Jul 1;35(13):1385-99. doi: 10.15252/embj.201593458. Epub 2016 May 27. EMBO J. 2016. PMID: 27234299 Free PMC article.
cGAS is activated by DNA in a length-dependent manner.
Luecke S, Holleufer A, Christensen MH, Jønsson KL, Boni GA, Sørensen LK, Johannsen M, Jakobsen MR, Hartmann R, Paludan SR. Luecke S, et al. Among authors: hartmann r. EMBO Rep. 2017 Oct;18(10):1707-1715. doi: 10.15252/embr.201744017. Epub 2017 Aug 10. EMBO Rep. 2017. PMID: 28801534 Free PMC article.
The role of IFN in the development of NAFLD and NASH.
Møhlenberg M, Terczynska-Dyla E, Thomsen KL, George J, Eslam M, Grønbæk H, Hartmann R. Møhlenberg M, et al. Among authors: hartmann r. Cytokine. 2019 Dec;124:154519. doi: 10.1016/j.cyto.2018.08.013. Epub 2018 Aug 21. Cytokine. 2019. PMID: 30139548 Review.
1,245 results