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Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility.
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius D, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: hartman j. J Med Chem. 2024 May 10. doi: 10.1021/acs.jmedchem.3c02413. Online ahead of print. J Med Chem. 2024. PMID: 38729623
Impact and timing of pulmonary rehabilitation in patients undergoing bronchoscopic lung volume reduction with endobronchial valves: A multicentre randomized controlled trial in patients with severe emphysema.
van der Molen MC, Posthuma R, Hartman JE, van der Vaart H, Bij de Vaate E, Vaes AW, van den Borst B, van Ranst D, Spruit MA, Vanfleteren LEGW, Slebos DJ; SoLVE consortium group. van der Molen MC, et al. Among authors: hartman je. Respirology. 2024 May 8. doi: 10.1111/resp.14734. Online ahead of print. Respirology. 2024. PMID: 38720189
Addition of Contrast-enhanced Mammography to Tomosynthesis for Breast Cancer Detection in Women with a Personal History of Breast Cancer: Prospective TOCEM Trial Interim Analysis.
Berg WA, Berg JM, Bandos AI, Vargo A, Chough DM, Lu AH, Ganott MA, Kelly AE, Nair BE, Hartman JY, Waheed U, Hakim CM, Harnist KS, Reginella RF, Shinde DD, Carlin BA, Cohen CS, Wallace LP, Sumkin JH, Zuley ML. Berg WA, et al. Among authors: hartman jy. Radiology. 2024 Apr;311(1):e231991. doi: 10.1148/radiol.231991. Radiology. 2024. PMID: 38687218
A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells.
Fonseca P, Cui W, Struyf N, Tong L, Chaurasiya A, Casagrande F, Zhao H, Fernando D, Chen X, Tobin NP, Seashore-Ludlow B, Lundqvist A, Hartman J, Göndör A, Östling P, Holmgren L. Fonseca P, et al. Among authors: hartman j. J Exp Clin Cancer Res. 2024 Apr 9;43(1):107. doi: 10.1186/s13046-024-03031-w. J Exp Clin Cancer Res. 2024. PMID: 38594748 Free PMC article.
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease.
Donkervoort S, van de Locht M, Ronchi D, Reunert J, McLean CA, Zaki M, Orbach R, de Winter JM, Conijn S, Hoomoedt D, Neto OLA, Magri F, Viaene AN, Foley AR, Gorokhova S, Bolduc V, Hu Y, Acquaye N, Napoli L, Park JH, Immadisetty K, Miles LB, Essawi M, McModie S, Ferreira LF, Zanotti S, Neuhaus SB, Medne L, ElBagoury N, Johnson KR, Zhang Y, Laing NG, Davis MR, Bryson-Richardson RJ, Hwee DT, Hartman JJ, Malik FI, Kekenes-Huskey PM, Comi GP, Sharaf-Eldin W, Marquardt T, Ravenscroft G, Bönnemann CG, Ottenheijm CAC. Donkervoort S, et al. Among authors: hartman jj. Sci Transl Med. 2024 Apr 3;16(741):eadg2841. doi: 10.1126/scitranslmed.adg2841. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569017
1,099 results