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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Rolando M, Escoll P, Nora T, Botti J, Boitez V, Bedia C, Daniels C, Abraham G, Stogios PJ, Skarina T, Christophe C, Dervins-Ravault D, Cazalet C, Hilbi H, Rupasinghe TW, Tull D, McConville MJ, Ong SY, Hartland EL, Codogno P, Levade T, Naderer T, Savchenko A, Buchrieser C. Rolando M, et al. Among authors: hartland el. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1901-6. doi: 10.1073/pnas.1522067113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831115 Free PMC article.
Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides.
Clements A, Tull D, Jenney AW, Farn JL, Kim SH, Bishop RE, McPhee JB, Hancock RE, Hartland EL, Pearse MJ, Wijburg OL, Jackson DC, McConville MJ, Strugnell RA. Clements A, et al. Among authors: hartland el. J Biol Chem. 2007 May 25;282(21):15569-77. doi: 10.1074/jbc.M701454200. Epub 2007 Mar 19. J Biol Chem. 2007. PMID: 17371870 Free PMC article.
Significant role for ladC in initiation of Legionella pneumophila infection.
Newton HJ, Sansom FM, Dao J, Cazalet C, Bruggemann H, Albert-Weissenberger C, Buchrieser C, Cianciotto NP, Hartland EL. Newton HJ, et al. Among authors: hartland el. Infect Immun. 2008 Jul;76(7):3075-85. doi: 10.1128/IAI.00209-08. Epub 2008 Apr 21. Infect Immun. 2008. PMID: 18426879 Free PMC article.
Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases.
Vivian JP, Riedmaier P, Ge H, Le Nours J, Sansom FM, Wilce MC, Byres E, Dias M, Schmidberger JW, Cowan PJ, d'Apice AJ, Hartland EL, Rossjohn J, Beddoe T. Vivian JP, et al. Among authors: hartland el. Structure. 2010 Feb 10;18(2):228-38. doi: 10.1016/j.str.2009.11.014. Structure. 2010. PMID: 20159467 Free article.
Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.
Cazalet C, Gomez-Valero L, Rusniok C, Lomma M, Dervins-Ravault D, Newton HJ, Sansom FM, Jarraud S, Zidane N, Ma L, Bouchier C, Etienne J, Hartland EL, Buchrieser C. Cazalet C, et al. Among authors: hartland el. PLoS Genet. 2010 Feb 19;6(2):e1000851. doi: 10.1371/journal.pgen.1000851. PLoS Genet. 2010. PMID: 20174605 Free PMC article.
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.
Lomma M, Dervins-Ravault D, Rolando M, Nora T, Newton HJ, Sansom FM, Sahr T, Gomez-Valero L, Jules M, Hartland EL, Buchrieser C. Lomma M, et al. Among authors: hartland el. Cell Microbiol. 2010 Sep 1;12(9):1272-91. doi: 10.1111/j.1462-5822.2010.01467.x. Epub 2010 Mar 25. Cell Microbiol. 2010. PMID: 20345489
Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins.
Schroeder GN, Petty NK, Mousnier A, Harding CR, Vogrin AJ, Wee B, Fry NK, Harrison TG, Newton HJ, Thomson NR, Beatson SA, Dougan G, Hartland EL, Frankel G. Schroeder GN, et al. Among authors: hartland el. J Bacteriol. 2010 Nov;192(22):6001-16. doi: 10.1128/JB.00778-10. Epub 2010 Sep 10. J Bacteriol. 2010. PMID: 20833813 Free PMC article.
157 results