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NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.
Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG. Baig MS, et al. Among authors: hart pc. J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31. J Exp Med. 2015. PMID: 26324446 Free PMC article.
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. He C, et al. Among authors: hart pc. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591207 Free PMC article.
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR. Lee J, et al. Among authors: hart pc. Nature. 2019 Apr;568(7751):254-258. doi: 10.1038/s41586-019-1005-x. Epub 2019 Mar 6. Nature. 2019. PMID: 30842661 Free PMC article.
Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
Coelho DR, Palma FR, Paviani V, He C, Danes JM, Huang Y, Calado JCP, Hart PC, Furdui CM, Poole LB, Schipma MJ, Bonini MG. Coelho DR, et al. Among authors: hart pc. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2110348119. doi: 10.1073/pnas.2110348119. Epub 2022 Jul 14. Proc Natl Acad Sci U S A. 2022. PMID: 35858297 Free PMC article.
32 results