Harrison RA - Search Results

1

In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.

Menzies SK, Clare RH, Xie C, Westhorpe A, Hall SR, Edge RJ, Alsolaiss J, Crittenden E, Marriott AE, Harrison RA, Kool J, Casewell NR. Menzies SK, et al. Among authors: harrison ra. Toxicon X. 2022 Mar 18;14:100118. doi: 10.1016/j.toxcx.2022.100118. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35321116 Free PMC article.

2

Cloning of a prothrombin activator-like metalloproteinase from the West African saw-scaled viper, Echis ocellatus.

Hasson SS, Theakston RD, Harrison RA. Hasson SS, et al. Among authors: harrison ra. Toxicon. 2003 Nov;42(6):629-34. doi: 10.1016/j.toxicon.2003.08.009. Toxicon. 2003. PMID: 14602118

3

Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.

Casewell NR, Harrison RA, Wüster W, Wagstaff SC. Casewell NR, et al. Among authors: harrison ra. BMC Genomics. 2009 Nov 30;10:564. doi: 10.1186/1471-2164-10-564. BMC Genomics. 2009. PMID: 19948012 Free PMC article.

4

Analysis of camelid antibodies for antivenom development: Neutralisation of venom-induced pathology.

Cook DA, Owen T, Wagstaff SC, Kinne J, Wernery U, Harrison RA. Cook DA, et al. Among authors: harrison ra. Toxicon. 2010 Sep 1;56(3):373-80. doi: 10.1016/j.toxicon.2010.04.005. Epub 2010 Apr 20. Toxicon. 2010. PMID: 20412814

5

Analysis of camelid IgG for antivenom development: Immunoreactivity and preclinical neutralisation of venom-induced pathology by IgG subclasses, and the effect of heat treatment.

Cook DA, Samarasekara CL, Wagstaff SC, Kinne J, Wernery U, Harrison RA. Cook DA, et al. Among authors: harrison ra. Toxicon. 2010 Sep 15;56(4):596-603. doi: 10.1016/j.toxicon.2010.06.004. Epub 2010 Jun 12. Toxicon. 2010. PMID: 20547172

6

Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom.

Casewell NR, Cook DA, Wagstaff SC, Nasidi A, Durfa N, Wüster W, Harrison RA. Casewell NR, et al. Among authors: harrison ra. PLoS Negl Trop Dis. 2010 Oct 26;4(10):e851. doi: 10.1371/journal.pntd.0000851. PLoS Negl Trop Dis. 2010. PMID: 21049058 Free PMC article.

7

Gene tree parsimony of multilocus snake venom protein families reveals species tree conflict as a result of multiple parallel gene loss.

Casewell NR, Wagstaff SC, Harrison RA, Wüster W. Casewell NR, et al. Among authors: harrison ra. Mol Biol Evol. 2011 Mar;28(3):1157-72. doi: 10.1093/molbev/msq302. Epub 2010 Nov 8. Mol Biol Evol. 2011. PMID: 21062752

8

Domain loss facilitates accelerated evolution and neofunctionalization of duplicate snake venom metalloproteinase toxin genes.

Casewell NR, Wagstaff SC, Harrison RA, Renjifo C, Wüster W. Casewell NR, et al. Among authors: harrison ra. Mol Biol Evol. 2011 Sep;28(9):2637-49. doi: 10.1093/molbev/msr091. Epub 2011 Apr 4. Mol Biol Evol. 2011. PMID: 21478373

9

Research strategies to improve snakebite treatment: challenges and progress.

Harrison RA, Cook DA, Renjifo C, Casewell NR, Currier RB, Wagstaff SC. Harrison RA, et al. J Proteomics. 2011 Aug 24;74(9):1768-80. doi: 10.1016/j.jprot.2011.06.019. Epub 2011 Jun 25. J Proteomics. 2011. PMID: 21723969

10

Complex cocktails: the evolutionary novelty of venoms.

Casewell NR, Wüster W, Vonk FJ, Harrison RA, Fry BG. Casewell NR, et al. Among authors: harrison ra. Trends Ecol Evol. 2013 Apr;28(4):219-29. doi: 10.1016/j.tree.2012.10.020. Epub 2012 Dec 5. Trends Ecol Evol. 2013. PMID: 23219381 Review.

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