Harris DA - Search Results

1

Prion protein at the crossroads of physiology and disease.

Biasini E, Turnbaugh JA, Unterberger U, Harris DA. Biasini E, et al. Among authors: harris da. Trends Neurosci. 2012 Feb;35(2):92-103. doi: 10.1016/j.tins.2011.10.002. Epub 2011 Dec 1. Trends Neurosci. 2012. PMID: 22137337 Free PMC article. Review.

2

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation.

Drisaldi B, Stewart RS, Adles C, Stewart LR, Quaglio E, Biasini E, Fioriti L, Chiesa R, Harris DA. Drisaldi B, et al. Among authors: harris da. J Biol Chem. 2003 Jun 13;278(24):21732-43. doi: 10.1074/jbc.M213247200. Epub 2003 Mar 26. J Biol Chem. 2003. PMID: 12663673 Free article.

3

The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species.

Fioriti L, Quaglio E, Massignan T, Colombo L, Stewart RS, Salmona M, Harris DA, Forloni G, Chiesa R. Fioriti L, et al. Among authors: harris da. Mol Cell Neurosci. 2005 Jan;28(1):165-76. doi: 10.1016/j.mcn.2004.09.006. Mol Cell Neurosci. 2005. PMID: 15607951

4

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans.

Yin S, Pham N, Yu S, Li C, Wong P, Chang B, Kang SC, Biasini E, Tien P, Harris DA, Sy MS. Yin S, et al. Among authors: harris da. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7546-51. doi: 10.1073/pnas.0610827104. Epub 2007 Apr 24. Proc Natl Acad Sci U S A. 2007. PMID: 17456603 Free PMC article.

5

Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion.

Biasini E, Medrano AZ, Thellung S, Chiesa R, Harris DA. Biasini E, et al. Among authors: harris da. J Neurochem. 2008 Mar;104(5):1293-308. doi: 10.1111/j.1471-4159.2007.05082.x. Epub 2007 Nov 21. J Neurochem. 2008. PMID: 18034781 Free article.

6

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

Biasini E, Seegulam ME, Patti BN, Solforosi L, Medrano AZ, Christensen HM, Senatore A, Chiesa R, Williamson RA, Harris DA. Biasini E, et al. Among authors: harris da. J Neurochem. 2008 Jun 1;105(6):2190-204. doi: 10.1111/j.1471-4159.2008.05306.x. J Neurochem. 2008. PMID: 18298665 Free article.

7

GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice.

Medrano AZ, Barmada SJ, Biasini E, Harris DA. Medrano AZ, et al. Among authors: harris da. Neurobiol Dis. 2008 Jul;31(1):20-32. doi: 10.1016/j.nbd.2008.03.006. Epub 2008 Apr 7. Neurobiol Dis. 2008. PMID: 18514536 Free PMC article.

8

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

Chiesa R, Piccardo P, Biasini E, Ghetti B, Harris DA. Chiesa R, et al. Among authors: harris da. J Neurosci. 2008 Dec 3;28(49):13258-67. doi: 10.1523/JNEUROSCI.3109-08.2008. J Neurosci. 2008. PMID: 19052217 Free PMC article.

9

Immunopurification of pathological prion protein aggregates.

Biasini E, Tapella L, Mantovani S, Stravalaci M, Gobbi M, Harris DA, Chiesa R. Biasini E, et al. Among authors: harris da. PLoS One. 2009 Nov 12;4(11):e7816. doi: 10.1371/journal.pone.0007816. PLoS One. 2009. PMID: 19915706 Free PMC article.

10

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

Massignan T, Stewart RS, Biasini E, Solomon IH, Bonetto V, Chiesa R, Harris DA. Massignan T, et al. Among authors: harris da. J Biol Chem. 2010 Mar 5;285(10):7752-65. doi: 10.1074/jbc.M109.064949. Epub 2009 Nov 24. J Biol Chem. 2010. PMID: 19940127 Free PMC article.

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