Harris AL - Search Results

1

Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing.

Harris AL, Contreras JE. Harris AL, et al. Front Physiol. 2014 Mar 31;5:113. doi: 10.3389/fphys.2014.00113. eCollection 2014. Front Physiol. 2014. PMID: 24744733 Free PMC article. Review.

2

Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).

Lopez W, Gonzalez J, Liu Y, Harris AL, Contreras JE. Lopez W, et al. Among authors: harris al. J Gen Physiol. 2013 Jul;142(1):23-35. doi: 10.1085/jgp.201210893. J Gen Physiol. 2013. PMID: 23797420 Free PMC article.

3

Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules.

Tong X, Lopez W, Ramachandran J, Ayad WA, Liu Y, Lopez-Rodriguez A, Harris AL, Contreras JE. Tong X, et al. Among authors: harris al. J Gen Physiol. 2015 Sep;146(3):245-54. doi: 10.1085/jgp.201511375. J Gen Physiol. 2015. PMID: 26324677 Free PMC article.

4

Mechanism of gating by calcium in connexin hemichannels.

Lopez W, Ramachandran J, Alsamarah A, Luo Y, Harris AL, Contreras JE. Lopez W, et al. Among authors: harris al. Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7986-E7995. doi: 10.1073/pnas.1609378113. Epub 2016 Nov 21. Proc Natl Acad Sci U S A. 2016. PMID: 27872296 Free PMC article.

5

The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening.

Valdez Capuccino JM, Chatterjee P, García IE, Botello-Smith WM, Zhang H, Harris AL, Luo Y, Contreras JE. Valdez Capuccino JM, et al. Among authors: harris al. J Gen Physiol. 2019 Mar 4;151(3):328-341. doi: 10.1085/jgp.201812219. Epub 2018 Dec 7. J Gen Physiol. 2019. PMID: 30530766 Free PMC article.

6

A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels.

Gaete PS, Lillo MA, López W, Liu Y, Jiang W, Luo Y, Harris AL, Contreras JE. Gaete PS, et al. Among authors: harris al. J Gen Physiol. 2020 Nov 2;152(11):e202012607. doi: 10.1085/jgp.202012607. J Gen Physiol. 2020. PMID: 33074302 Free PMC article.

7

Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels.

Lopez W, Liu Y, Harris AL, Contreras JE. Lopez W, et al. Among authors: harris al. Channels (Austin). 2014;8(1):1-4. doi: 10.4161/chan.26789. Epub 2013 Oct 14. Channels (Austin). 2014. PMID: 24126106 Free PMC article.

8

Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization.

Trease AJ, Capuccino JMV, Contreras J, Harris AL, Sorgen PL. Trease AJ, et al. Among authors: harris al. J Mol Cell Cardiol. 2017 Oct;111:69-80. doi: 10.1016/j.yjmcc.2017.07.010. Epub 2017 Jul 25. J Mol Cell Cardiol. 2017. PMID: 28754342 Free PMC article.

9

Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning.

Jiang W, Lin YC, Botello-Smith W, Contreras JE, Harris AL, Maragliano L, Luo YL. Jiang W, et al. Among authors: harris al. Biophys J. 2021 Aug 3;120(15):2969-2983. doi: 10.1016/j.bpj.2021.06.024. Epub 2021 Jun 30. Biophys J. 2021. PMID: 34214529 Free PMC article.

10

Electrical coupling and its channels.

Harris AL. Harris AL. J Gen Physiol. 2018 Dec 3;150(12):1606-1639. doi: 10.1085/jgp.201812203. Epub 2018 Nov 2. J Gen Physiol. 2018. PMID: 30389716 Free PMC article. Review.

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