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The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.
Thomas RS, Bahadori T, Buckley TJ, Cowden J, Deisenroth C, Dionisio KL, Frithsen JB, Grulke CM, Gwinn MR, Harrill JA, Higuchi M, Houck KA, Hughes MF, Hunter ES, Isaacs KK, Judson RS, Knudsen TB, Lambert JC, Linnenbrink M, Martin TM, Newton SR, Padilla S, Patlewicz G, Paul-Friedman K, Phillips KA, Richard AM, Sams R, Shafer TJ, Setzer RW, Shah I, Simmons JE, Simmons SO, Singh A, Sobus JR, Strynar M, Swank A, Tornero-Valez R, Ulrich EM, Villeneuve DL, Wambaugh JF, Wetmore BA, Williams AJ. Thomas RS, et al. Among authors: harrill ja. Toxicol Sci. 2019 Jun 1;169(2):317-332. doi: 10.1093/toxsci/kfz058. Toxicol Sci. 2019. PMID: 30835285 Free PMC article.
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example.
Nyffeler J, Willis C, Harris FR, Taylor LW, Judson R, Everett LJ, Harrill JA. Nyffeler J, et al. Among authors: harrill ja. Toxicol Appl Pharmacol. 2022 Jun 1;444:116032. doi: 10.1016/j.taap.2022.116032. Epub 2022 Apr 26. Toxicol Appl Pharmacol. 2022. PMID: 35483669 Free PMC article.
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments.
Nyffeler J, Willis C, Harris FR, Foster MJ, Chambers B, Culbreth M, Brockway RE, Davidson-Fritz S, Dawson D, Shah I, Friedman KP, Chang D, Everett LJ, Wambaugh JF, Patlewicz G, Harrill JA. Nyffeler J, et al. Among authors: harrill ja. Toxicol Appl Pharmacol. 2023 Jun 1;468:116513. doi: 10.1016/j.taap.2023.116513. Epub 2023 Apr 11. Toxicol Appl Pharmacol. 2023. PMID: 37044265
From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow.
Reardon AJF, Farmahin R, Williams A, Meier MJ, Addicks GC, Yauk CL, Matteo G, Atlas E, Harrill J, Everett LJ, Shah I, Judson R, Ramaiahgari S, Ferguson SS, Barton-Maclaren TS. Reardon AJF, et al. Front Toxicol. 2023 May 23;5:1194895. doi: 10.3389/ftox.2023.1194895. eCollection 2023. Front Toxicol. 2023. PMID: 37288009 Free PMC article.
68 results