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New approach methodologies in human regulatory toxicology - Not if, but how and when!
Schmeisser S, Miccoli A, von Bergen M, Berggren E, Braeuning A, Busch W, Desaintes C, Gourmelon A, Grafström R, Harrill J, Hartung T, Herzler M, Kass GEN, Kleinstreuer N, Leist M, Luijten M, Marx-Stoelting P, Poetz O, van Ravenzwaay B, Roggeband R, Rogiers V, Roth A, Sanders P, Thomas RS, Marie Vinggaard A, Vinken M, van de Water B, Luch A, Tralau T. Schmeisser S, et al. Among authors: harrill j. Environ Int. 2023 Aug;178:108082. doi: 10.1016/j.envint.2023.108082. Epub 2023 Jul 4. Environ Int. 2023. PMID: 37422975 Free article. Review.
The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.
Thomas RS, Bahadori T, Buckley TJ, Cowden J, Deisenroth C, Dionisio KL, Frithsen JB, Grulke CM, Gwinn MR, Harrill JA, Higuchi M, Houck KA, Hughes MF, Hunter ES, Isaacs KK, Judson RS, Knudsen TB, Lambert JC, Linnenbrink M, Martin TM, Newton SR, Padilla S, Patlewicz G, Paul-Friedman K, Phillips KA, Richard AM, Sams R, Shafer TJ, Setzer RW, Shah I, Simmons JE, Simmons SO, Singh A, Sobus JR, Strynar M, Swank A, Tornero-Valez R, Ulrich EM, Villeneuve DL, Wambaugh JF, Wetmore BA, Williams AJ. Thomas RS, et al. Among authors: harrill ja. Toxicol Sci. 2019 Jun 1;169(2):317-332. doi: 10.1093/toxsci/kfz058. Toxicol Sci. 2019. PMID: 30835285 Free PMC article.
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach SS, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M. Harrill JA, et al. Regul Toxicol Pharmacol. 2021 Oct;125:105020. doi: 10.1016/j.yrtph.2021.105020. Epub 2021 Jul 29. Regul Toxicol Pharmacol. 2021. PMID: 34333066 Free PMC article.
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity.
Gant TW, Auerbach SS, Von Bergen M, Bouhifd M, Botham PA, Caiment F, Currie RA, Harrill J, Johnson K, Li D, Rouquie D, van Ravenzwaay B, Sistare F, Tralau T, Viant MR, van de Laan JW, Yauk C. Gant TW, et al. Among authors: harrill j. Arch Toxicol. 2023 Aug;97(8):2291-2302. doi: 10.1007/s00204-023-03522-3. Epub 2023 Jun 9. Arch Toxicol. 2023. PMID: 37296313 Free PMC article.
High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes.
Rogers JD, Leusch FDL, Chambers B, Daniels KD, Everett LJ, Judson R, Maruya K, Mehinto AC, Neale PA, Paul-Friedman K, Thomas R, Snyder SA, Harrill J. Rogers JD, et al. Among authors: harrill j. Environ Sci Technol. 2024 Jan 30;58(4):2027-2037. doi: 10.1021/acs.est.3c07525. Epub 2024 Jan 18. Environ Sci Technol. 2024. PMID: 38235672
74 results