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SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis.
Barbayianni I, Kanellopoulou P, Fanidis D, Nastos D, Ntouskou ED, Galaris A, Harokopos V, Hatzis P, Tsitoura E, Homer R, Kaminski N, Antoniou KM, Crestani B, Tzouvelekis A, Aidinis V. Barbayianni I, et al. Among authors: harokopos v. Nat Commun. 2023 Sep 21;14(1):5882. doi: 10.1038/s41467-023-41614-x. Nat Commun. 2023. PMID: 37735172 Free PMC article.
Hepatocyte autotaxin expression promotes liver fibrosis and cancer.
Kaffe E, Katsifa A, Xylourgidis N, Ninou I, Zannikou M, Harokopos V, Foka P, Dimitriadis A, Evangelou K, Moulas AN, Georgopoulou U, Gorgoulis VG, Dalekos GN, Aidinis V. Kaffe E, et al. Among authors: harokopos v. Hepatology. 2017 Apr;65(4):1369-1383. doi: 10.1002/hep.28973. Epub 2017 Feb 7. Hepatology. 2017. PMID: 27981605
The Autotaxin-Lysophosphatidic Acid Axis Promotes Lung Carcinogenesis.
Magkrioti C, Oikonomou N, Kaffe E, Mouratis MA, Xylourgidis N, Barbayianni I, Megadoukas P, Harokopos V, Valavanis C, Chun J, Kosma A, Stathopoulos GT, Bouros E, Bouros D, Syrigos K, Aidinis V. Magkrioti C, et al. Among authors: harokopos v. Cancer Res. 2018 Jul 1;78(13):3634-3644. doi: 10.1158/0008-5472.CAN-17-3797. Epub 2018 May 3. Cancer Res. 2018. PMID: 29724718
Mutant KRAS promotes malignant pleural effusion formation.
Agalioti T, Giannou AD, Krontira AC, Kanellakis NI, Kati D, Vreka M, Pepe M, Spella M, Lilis I, Zazara DE, Nikolouli E, Spiropoulou N, Papadakis A, Papadia K, Voulgaridis A, Harokopos V, Stamou P, Meiners S, Eickelberg O, Snyder LA, Antimisiaris SG, Kardamakis D, Psallidas I, Marazioti A, Stathopoulos GT. Agalioti T, et al. Among authors: harokopos v. Nat Commun. 2017 May 16;8:15205. doi: 10.1038/ncomms15205. Nat Commun. 2017. PMID: 28508873 Free PMC article.
Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis.
Aidinis V, Carninci P, Armaka M, Witke W, Harokopos V, Pavelka N, Koczan D, Argyropoulos C, Thwin MM, Möller S, Waki K, Gopalakrishnakone P, Ricciardi-Castagnoli P, Thiesen HJ, Hayashizaki Y, Kollias G. Aidinis V, et al. Among authors: harokopos v. PLoS Genet. 2005 Oct;1(4):e48. doi: 10.1371/journal.pgen.0010048. Epub 2005 Oct 28. PLoS Genet. 2005. PMID: 16254600 Free PMC article.
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