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Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis.
Debowski AW, Bzdyl NM, Thomas DR, Scott NE, Jenkins CH, Iwasaki J, Kibble EA, Khoo CA, Scheuplein NJ, Seibel PM, Lohr T, Metters G, Bond CS, Norville IH, Stubbs KA, Harmer NJ, Holzgrabe U, Newton HJ, Sarkar-Tyson M. Debowski AW, et al. Among authors: harmer nj. PLoS Pathog. 2023 Jul 3;19(7):e1011491. doi: 10.1371/journal.ppat.1011491. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37399210 Free PMC article.
Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages.
Iwasaki J, Bzdyl NM, Lin-Sullivan DJM, Scheuplein NJ, Dueñas ME, de Jong E, Harmer NJ, Holzgrabe U, Sarkar-Tyson M. Iwasaki J, et al. Among authors: harmer nj. Front Cell Infect Microbiol. 2024 Mar 25;14:1353682. doi: 10.3389/fcimb.2024.1353682. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38590438 Free PMC article.
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Freda I, Exertier C, Barile A, Chaves-Sanjuan A, Vega MV, Isupov MN, Harmer NJ, Gugole E, Swuec P, Bolognesi M, Scipioni A, Savino C, Di Salvo ML, Contestabile R, Vallone B, Tramonti A, Montemiglio LC. Freda I, et al. Among authors: harmer nj. Nucleic Acids Res. 2023 Aug 25;51(15):8237-8254. doi: 10.1093/nar/gkad552. Nucleic Acids Res. 2023. PMID: 37378428 Free PMC article.
The natriuretic peptide receptor agonist osteocrin disperses Pseudomonas aeruginosa biofilm.
Louis M, Tahrioui A, Tremlett CJ, Clamens T, Leprince J, Lefranc B, Kipnis E, Grandjean T, Bouffartigues E, Barreau M, Defontaine F, Cornelis P, Feuilloley MGJ, Harmer NJ, Chevalier S, Lesouhaitier O. Louis M, et al. Among authors: harmer nj. Biofilm. 2023 May 19;5:100131. doi: 10.1016/j.bioflm.2023.100131. eCollection 2023 Dec. Biofilm. 2023. PMID: 37252226 Free PMC article.
Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
Iwasaki J, Lorimer DD, Vivoli-Vega M, Kibble EA, Peacock CS, Abendroth J, Mayclin SJ, Dranow DM, Pierce PG, Fox D, Lewis M, Bzdyl NM, Kristensen SS, Inglis TJJ, Kahler CM, Bond CS, Hasenkopf A, Seufert F, Schmitz J, Marshall LE, Scott AE, Norville IH, Myler PJ, Holzgrabe U, Harmer NJ, Sarkar-Tyson M. Iwasaki J, et al. Among authors: harmer nj. J Antimicrob Chemother. 2022 May 29;77(6):1625-1634. doi: 10.1093/jac/dkac065. J Antimicrob Chemother. 2022. PMID: 35245364 Free PMC article.
51 results