Harmer JR - Search Results

1

Characterization of a highly efficient antibiotic-degrading metallo-β-lactamase obtained from an uncultured member of a permafrost community.

Pedroso MM, Selleck C, Enculescu C, Harmer JR, Mitić N, Craig WR, Helweh W, Hugenholtz P, Tyson GW, Tierney DL, Larrabee JA, Schenk G. Pedroso MM, et al. Among authors: harmer jr. Metallomics. 2017 Aug 16;9(8):1157-1168. doi: 10.1039/c7mt00195a. Metallomics. 2017. PMID: 28749495

2

AIM-1: An Antibiotic-Degrading Metallohydrolase That Displays Mechanistic Flexibility.

Selleck C, Larrabee JA, Harmer J, Guddat LW, Mitić N, Helweh W, Ollis DL, Craig WR, Tierney DL, Monteiro Pedroso M, Schenk G. Selleck C, et al. Chemistry. 2016 Dec 5;22(49):17704-17714. doi: 10.1002/chem.201602762. Epub 2016 Oct 25. Chemistry. 2016. PMID: 27778387

3

Reaction mechanism of the metallohydrolase CpsB from Streptococcus pneumoniae, a promising target for novel antimicrobial agents.

Monteiro Pedroso M, Selleck C, Bilyj J, Harmer JR, Gahan LR, Mitić N, Standish AJ, Tierney DL, Larrabee JA, Schenk G. Monteiro Pedroso M, et al. Among authors: harmer jr. Dalton Trans. 2017 Oct 10;46(39):13194-13201. doi: 10.1039/c7dt01350g. Dalton Trans. 2017. PMID: 28573276

4

A New Mixed-Valence Mn(II)Mn(III) Compound With Catalase and Superoxide Dismutase Activities.

Costa RO, Ferreira SS, Pereira CA, Harmer JR, Noble CJ, Schenk G, Franco RWA, Resende JALC, Comba P, Roberts AE, Fernandes C, Horn A Jr. Costa RO, et al. Among authors: harmer jr. Front Chem. 2018 Nov 5;6:491. doi: 10.3389/fchem.2018.00491. eCollection 2018. Front Chem. 2018. PMID: 30456211 Free PMC article.

5

Dihydroxy-Acid Dehydratases From Pathogenic Bacteria: Emerging Drug Targets to Combat Antibiotic Resistance.

Bayaraa T, Gaete J, Sutiono S, Kurz J, Lonhienne T, Harmer JR, Bernhardt PV, Sieber V, Guddat L, Schenk G. Bayaraa T, et al. Among authors: harmer jr. Chemistry. 2022 Aug 4;28(44):e202200927. doi: 10.1002/chem.202200927. Epub 2022 Jun 16. Chemistry. 2022. PMID: 35535733 Free PMC article.

6

Engineering proton conductivity in melanin using metal doping.

Mostert AB, Rienecker SB, Sheliakina M, Zierep P, Hanson GR, Harmer JR, Schenk G, Meredith P. Mostert AB, et al. Among authors: harmer jr. J Mater Chem B. 2020 Sep 21;8(35):8050-8060. doi: 10.1039/d0tb01390k. Epub 2020 Aug 11. J Mater Chem B. 2020. PMID: 32780061

7

Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes.

Struwe MA, Kalimuthu P, Luo Z, Zhong Q, Ellis D, Yang J, Khadanand KC, Harmer JR, Kirk ML, McEwan AG, Clement B, Bernhardt PV, Kobe B, Kappler U. Struwe MA, et al. Among authors: harmer jr. J Biol Chem. 2021 Jan-Jun;296:100672. doi: 10.1016/j.jbc.2021.100672. Epub 2021 Apr 20. J Biol Chem. 2021. PMID: 33887324 Free PMC article.

8

The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions.

Hsiao JC, McGrath AP, Kielmann L, Kalimuthu P, Darain F, Bernhardt PV, Harmer J, Lee M, Meyers K, Maher MJ, Kappler U. Hsiao JC, et al. Biochim Biophys Acta Bioenerg. 2018 Jan;1859(1):19-27. doi: 10.1016/j.bbabio.2017.10.001. Epub 2017 Oct 3. Biochim Biophys Acta Bioenerg. 2018. PMID: 28986298 Free article.

9

A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA.

Luo Z, Morey JR, Deplazes E, Motygullina A, Tan A, Ganio K, Neville SL, Eleftheriadis N, Isselstein M, Pederick VG, Paton JC, Cordes T, Harmer JR, Kobe B, McDevitt CA. Luo Z, et al. Among authors: harmer jr. mBio. 2021 Feb 2;12(1):e01958-20. doi: 10.1128/mBio.01958-20. mBio. 2021. PMID: 33531394 Free PMC article.

10

Electrochemically driven catalysis of the bacterial molybdenum enzyme YiiM.

Kalimuthu P, Harmer JR, Baldauf M, Hassan AH, Kruse T, Bernhardt PV. Kalimuthu P, et al. Among authors: harmer jr. Biochim Biophys Acta Bioenerg. 2022 Mar 1;1863(3):148523. doi: 10.1016/j.bbabio.2021.148523. Epub 2021 Dec 16. Biochim Biophys Acta Bioenerg. 2022. PMID: 34921810 Free article.

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