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Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of Their in vitro Antiproliferative Effects.
Fodor KJ, Hutai D, Jernei T, Takács A, Szász Z, Sulyok-Eiler M, Harmat V, Oláh Szabó R, Schlosser G, Hudecz F, Kőhidai L, Csámpai A. Fodor KJ, et al. Among authors: harmat v. Molecules. 2020 Mar 31;25(7):1599. doi: 10.3390/molecules25071599. Molecules. 2020. PMID: 32244444 Free PMC article.
Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides.
Dürvanger Z, Boros E, Nagy ZA, Hegedüs R, Megyeri M, Dobó J, Gál P, Schlosser G, Ángyán AF, Gáspári Z, Perczel A, Harmat V, Mező G, Menyhárd DK, Pál G. Dürvanger Z, et al. Among authors: harmat v. ACS Chem Biol. 2022 Apr 15;17(4):969-986. doi: 10.1021/acschembio.2c00114. Epub 2022 Apr 4. ACS Chem Biol. 2022. PMID: 35378038 Free PMC article.
Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.
Menyhárd DK, Orgován Z, Szeltner Z, Szamosi I, Harmat V. Menyhárd DK, et al. Among authors: harmat v. Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):461-72. doi: 10.1107/S1399004714026819. Epub 2015 Feb 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25760596 Free article.
Structural Diversity in Calmodulin - Peptide Interactions.
Dürvanger Z, Harmat V. Dürvanger Z, et al. Among authors: harmat v. Curr Protein Pept Sci. 2019;20(11):1102-1111. doi: 10.2174/1389203720666190925101937. Curr Protein Pept Sci. 2019. PMID: 31553290 Review.
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
Héja D, Harmat V, Fodor K, Wilmanns M, Dobó J, Kékesi KA, Závodszky P, Gál P, Pál G. Héja D, et al. Among authors: harmat v. J Biol Chem. 2012 Jun 8;287(24):20290-300. doi: 10.1074/jbc.M112.354332. Epub 2012 Apr 16. J Biol Chem. 2012. PMID: 22511776 Free PMC article.
45 results