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Disrupted Cacna1c gene expression perturbs spontaneous Ca2+ activity causing abnormal brain development and increased anxiety.
Smedler E, Louhivuori L, Romanov RA, Masini D, Dehnisch Ellström I, Wang C, Caramia M, West Z, Zhang S, Rebellato P, Malmersjö S, Brusini I, Kanatani S, Fisone G, Harkany T, Uhlén P. Smedler E, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2108768119. doi: 10.1073/pnas.2108768119. Proc Natl Acad Sci U S A. 2022. PMID: 35135875 Free PMC article.
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.
Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, Galve-Roperh I, Harkany T. Mulder J, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8760-5. doi: 10.1073/pnas.0803545105. Epub 2008 Jun 18. Proc Natl Acad Sci U S A. 2008. PMID: 18562289 Free PMC article.
Orexin neurons use endocannabinoids to break obesity-induced inhibition.
Alpár A, Harkany T. Alpár A, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9625-6. doi: 10.1073/pnas.1307389110. Epub 2013 May 29. Proc Natl Acad Sci U S A. 2013. PMID: 23720305 Free PMC article. No abstract available.
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.
Zhang MD, Tortoriello G, Hsueh B, Tomer R, Ye L, Mitsios N, Borgius L, Grant G, Kiehn O, Watanabe M, Uhlén M, Mulder J, Deisseroth K, Harkany T, Hökfelt TG. Zhang MD, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1149-58. doi: 10.1073/pnas.1402318111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616509 Free PMC article.
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels.
Iannotti FA, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, Ambrosino P, Petrosino S, Czifra G, Bíró T, Harkany T, Taglialatela M, Di Marzo V. Iannotti FA, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2472-81. doi: 10.1073/pnas.1406728111. Epub 2014 Jun 3. Proc Natl Acad Sci U S A. 2014. PMID: 24927567 Free PMC article.
A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
Romanov RA, Alpár A, Zhang MD, Zeisel A, Calas A, Landry M, Fuszard M, Shirran SL, Schnell R, Dobolyi Á, Oláh M, Spence L, Mulder J, Martens H, Palkovits M, Uhlen M, Sitte HH, Botting CH, Wagner L, Linnarsson S, Hökfelt T, Harkany T. Romanov RA, et al. Among authors: harkany t. EMBO J. 2015 Jan 2;34(1):36-54. doi: 10.15252/embj.201488977. Epub 2014 Nov 27. EMBO J. 2015. PMID: 25430741 Free PMC article.
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture.
Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt TG, Dobrzyn A, Harkany T. Malenczyk K, et al. Among authors: harkany t. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94. doi: 10.1073/pnas.1519040112. Epub 2015 Oct 22. Proc Natl Acad Sci U S A. 2015. PMID: 26494286 Free PMC article.
187 results