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Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics.
Huang LS, Kotha SR, Avasarala S, VanScoyk M, Winn RA, Pennathur A, Yashaswini PS, Bandela M, Salgia R, Tyurina YY, Kagan VE, Zhu X, Reddy SP, Sudhadevi T, Punathil-Kannan PK, Harijith A, Ramchandran R, Bikkavilli RK, Natarajan V. Huang LS, et al. Among authors: harijith a. J Biol Chem. 2020 Sep 18;295(38):13393-13406. doi: 10.1074/jbc.RA120.012680. Epub 2020 Jul 30. J Biol Chem. 2020. PMID: 32732285 Free PMC article.
Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.
Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V. Harijith A, et al. Am J Pathol. 2013 Oct;183(4):1169-1182. doi: 10.1016/j.ajpath.2013.06.018. Epub 2013 Aug 8. Am J Pathol. 2013. PMID: 23933064 Free PMC article.
The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.
Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V. Huang LS, et al. Among authors: harijith a. Am J Respir Crit Care Med. 2014 Jun 1;189(11):1402-15. doi: 10.1164/rccm.201310-1917OC. Am J Respir Crit Care Med. 2014. PMID: 24779708 Free PMC article.
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.
Huang LS, Berdyshev EV, Tran JT, Xie L, Chen J, Ebenezer DL, Mathew B, Gorshkova I, Zhang W, Reddy SP, Harijith A, Wang G, Feghali-Bostwick C, Noth I, Ma SF, Zhou T, Ma W, Garcia JG, Natarajan V. Huang LS, et al. Among authors: harijith a. Thorax. 2015 Dec;70(12):1138-48. doi: 10.1136/thoraxjnl-2014-206684. Epub 2015 Aug 18. Thorax. 2015. PMID: 26286721 Free article.
Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
Harijith A, Pendyala S, Ebenezer DL, Ha AW, Fu P, Wang YT, Ma K, Toth PT, Berdyshev EV, Kanteti P, Natarajan V. Harijith A, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L337-51. doi: 10.1152/ajplung.00447.2015. Epub 2016 Jun 24. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27343196 Free PMC article.
36 results