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306 results

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Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine.
Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: hargreaves r. Neuroimage. 2012 Feb 15;59(4):3762-73. doi: 10.1016/j.neuroimage.2011.11.034. Epub 2011 Nov 18. Neuroimage. 2012. PMID: 22119647
Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects.
Becerra L, Upadhyay J, Chang PC, Bishop J, Anderson J, Baumgartner R, Schwarz AJ, Coimbra A, Wallin D, Nutile L, George E, Maier G, Sunkaraneni S, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Borsook D. Becerra L, et al. Among authors: hargreaves r. J Pharmacol Exp Ther. 2013 Apr;345(1):41-51. doi: 10.1124/jpet.112.201145. Epub 2013 Jan 31. J Pharmacol Exp Ther. 2013. PMID: 23370795 Clinical Trial.
A 'BOLD' experiment in defining the utility of fMRI in drug development.
Borsook D, Bleakman D, Hargreaves R, Upadhyay J, Schmidt KF, Becerra L. Borsook D, et al. Among authors: hargreaves r. Neuroimage. 2008 Aug 15;42(2):461-6. doi: 10.1016/j.neuroimage.2008.04.268. Epub 2008 Jun 10. Neuroimage. 2008. PMID: 18598770 Review. No abstract available.
Improved characterization of BOLD responses for evoked sensory stimuli.
Upadhyay J, Pendse G, Anderson J, Schwarz AJ, Baumgartner R, Coimbra A, Bishop J, Knudsen J, George E, Grachev I, Iyengar S, Bleakman D, Hargreaves R, Borsook D, Becerra L. Upadhyay J, et al. Among authors: hargreaves r. Neuroimage. 2010 Feb 1;49(3):2275-86. doi: 10.1016/j.neuroimage.2009.10.053. Epub 2009 Oct 23. Neuroimage. 2010. PMID: 19854280
Imaging drugs with and without clinical analgesic efficacy.
Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: hargreaves r. Neuropsychopharmacology. 2011 Dec;36(13):2659-73. doi: 10.1038/npp.2011.156. Epub 2011 Aug 17. Neuropsychopharmacology. 2011. PMID: 21849979 Free PMC article. Clinical Trial.
Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain.
Borsook D, Upadhyay J, Klimas M, Schwarz AJ, Coimbra A, Baumgartner R, George E, Potter WZ, Large T, Bleakman D, Evelhoch J, Iyengar S, Becerra L, Hargreaves RJ. Borsook D, et al. Among authors: hargreaves rj. Drug Discov Today. 2012 Sep;17(17-18):964-73. doi: 10.1016/j.drudis.2012.05.004. Epub 2012 May 10. Drug Discov Today. 2012. PMID: 22579743 Review.
Test-retest reliability of evoked heat stimulation BOLD fMRI.
Upadhyay J, Lemme J, Anderson J, Bleakman D, Large T, Evelhoch JL, Hargreaves R, Borsook D, Becerra L. Upadhyay J, et al. Among authors: hargreaves r. J Neurosci Methods. 2015 Sep 30;253:38-46. doi: 10.1016/j.jneumeth.2015.06.001. Epub 2015 Jun 10. J Neurosci Methods. 2015. PMID: 26072245
306 results