Hardy S - Search Results

1

Protein tyrosine phosphatases in cancer: friends and foes!

Labbé DP, Hardy S, Tremblay ML. Labbé DP, et al. Among authors: hardy s. Prog Mol Biol Transl Sci. 2012;106:253-306. doi: 10.1016/B978-0-12-396456-4.00009-2. Prog Mol Biol Transl Sci. 2012. PMID: 22340721 Review.

2

Physiological and oncogenic roles of the PRL phosphatases.

Hardy S, Kostantin E, Hatzihristidis T, Zolotarov Y, Uetani N, Tremblay ML. Hardy S, et al. FEBS J. 2018 Nov;285(21):3886-3908. doi: 10.1111/febs.14503. Epub 2018 May 27. FEBS J. 2018. PMID: 29770564 Free article. Review.

3

Inside the human cancer tyrosine phosphatome.

Julien SG, Dubé N, Hardy S, Tremblay ML. Julien SG, et al. Among authors: hardy s. Nat Rev Cancer. 2011 Jan;11(1):35-49. doi: 10.1038/nrc2980. Nat Rev Cancer. 2011. PMID: 21179176 Review.

4

Impact of oncogenic protein tyrosine phosphatases in cancer.

Hardy S, Julien SG, Tremblay ML. Hardy S, et al. Anticancer Agents Med Chem. 2012 Jan;12(1):4-18. doi: 10.2174/187152012798764741. Anticancer Agents Med Chem. 2012. PMID: 21707506 Review.

5

Protein tyrosine phosphatome metabolic screen identifies TC-PTP as a positive regulator of cancer cell bioenergetics and mitochondrial dynamics.

Vinette V, Aubry I, Insull H, Uetani N, Hardy S, Tremblay ML. Vinette V, et al. Among authors: hardy s. FASEB J. 2021 Jul;35(7):e21708. doi: 10.1096/fj.202100207R. FASEB J. 2021. PMID: 34169549

6

The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis.

Hardy S, Uetani N, Wong N, Kostantin E, Labbé DP, Bégin LR, Mes-Masson A, Miranda-Saavedra D, Tremblay ML. Hardy S, et al. Oncogene. 2015 Feb 19;34(8):986-95. doi: 10.1038/onc.2014.33. Epub 2014 Mar 17. Oncogene. 2015. PMID: 24632616

7

Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth.

Kostantin E, Hardy S, Valinsky WC, Kompatscher A, de Baaij JH, Zolotarov Y, Landry M, Uetani N, Martínez-Cruz LA, Hoenderop JG, Shrier A, Tremblay ML. Kostantin E, et al. Among authors: hardy s. J Biol Chem. 2016 May 13;291(20):10716-25. doi: 10.1074/jbc.M115.705863. Epub 2016 Mar 11. J Biol Chem. 2016. PMID: 26969161 Free PMC article.

8

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

Giménez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ereño-Orbea J, Martínez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, Müller D, Tremblay ML, Martínez-Cruz LA. Giménez-Mascarell P, et al. Among authors: hardy s. J Biol Chem. 2017 Jan 20;292(3):786-801. doi: 10.1074/jbc.M116.759944. Epub 2016 Nov 29. J Biol Chem. 2017. PMID: 27899452 Free PMC article.

9

Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain.

Wu CL, Hardy S, Aubry I, Landry M, Haggarty A, Saragovi HU, Tremblay ML. Wu CL, et al. Among authors: hardy s. PLoS One. 2017 May 30;12(5):e0178489. doi: 10.1371/journal.pone.0178489. eCollection 2017. PLoS One. 2017. PMID: 28558026 Free PMC article.

10

Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism.

Hardy S, Kostantin E, Wang SJ, Hristova T, Galicia-Vázquez G, Baranov PV, Pelletier J, Tremblay ML. Hardy S, et al. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2925-2934. doi: 10.1073/pnas.1815361116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718434 Free PMC article.

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