Hardwidge PR - Search Results

1

Repurposing Avasimibe to Inhibit Bacterial Glycosyltransferases.

Hasan MK, El Qaidi S, McDonald P, Roy A, Hardwidge PR. Hasan MK, et al. Among authors: hardwidge pr. Pathogens. 2022 Mar 17;11(3):370. doi: 10.3390/pathogens11030370. Pathogens. 2022. PMID: 35335693 Free PMC article.

2

SseL Deubiquitinates RPS3 to Inhibit Its Nuclear Translocation.

Wu M, El Qaidi S, Hardwidge PR. Wu M, et al. Among authors: hardwidge pr. Pathogens. 2018 Nov 7;7(4):86. doi: 10.3390/pathogens7040086. Pathogens. 2018. PMID: 30405005 Free PMC article.

3

YM155 Inhibits NleB and SseK Arginine Glycosyltransferase Activity.

Zhu C, El Qaidi S, McDonald P, Roy A, Hardwidge PR. Zhu C, et al. Among authors: hardwidge pr. Pathogens. 2021 Feb 23;10(2):253. doi: 10.3390/pathogens10020253. Pathogens. 2021. PMID: 33672424 Free PMC article.

4

The T3SS Effector Protease NleC Is Active within Citrobacter rodentium.

Hasan MK, El Qaidi S, Hardwidge PR. Hasan MK, et al. Among authors: hardwidge pr. Pathogens. 2021 May 12;10(5):589. doi: 10.3390/pathogens10050589. Pathogens. 2021. PMID: 34065796 Free PMC article.

5

Salmonella, E. coli, and Citrobacter Type III Secretion System Effector Proteins that Alter Host Innate Immunity.

El Qaidi S, Wu M, Zhu C, Hardwidge PR. El Qaidi S, et al. Among authors: hardwidge pr. Adv Exp Med Biol. 2019;1111:205-218. doi: 10.1007/5584_2018_289. Adv Exp Med Biol. 2019. PMID: 30411307 Review.

6

High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors.

El Qaidi S, Zhu C, McDonald P, Roy A, Maity PK, Rane D, Perera C, Hardwidge PR. El Qaidi S, et al. Among authors: hardwidge pr. Front Cell Infect Microbiol. 2018 Dec 18;8:435. doi: 10.3389/fcimb.2018.00435. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30619781 Free PMC article.

7

An intra-bacterial activity for a T3SS effector.

El Qaidi S, Scott NE, Hays MP, Geisbrecht BV, Watkins S, Hardwidge PR. El Qaidi S, et al. Among authors: hardwidge pr. Sci Rep. 2020 Jan 23;10(1):1073. doi: 10.1038/s41598-020-58062-y. Sci Rep. 2020. PMID: 31974499 Free PMC article.

8

Arginine glycosylation enhances methylglyoxal detoxification.

El Qaidi S, Scott NE, Hardwidge PR. El Qaidi S, et al. Among authors: hardwidge pr. Sci Rep. 2021 Feb 15;11(1):3834. doi: 10.1038/s41598-021-83437-0. Sci Rep. 2021. PMID: 33589708 Free PMC article.

9

Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.

Park JB, Kim YH, Yoo Y, Kim J, Jun SH, Cho JW, El Qaidi S, Walpole S, Monaco S, García-García AA, Wu M, Hays MP, Hurtado-Guerrero R, Angulo J, Hardwidge PR, Shin JS, Cho HS. Park JB, et al. Among authors: hardwidge pr. Nat Commun. 2018 Oct 16;9(1):4283. doi: 10.1038/s41467-018-06680-6. Nat Commun. 2018. PMID: 30327479 Free PMC article.

10

NleB/SseK-catalyzed arginine-glycosylation and enteropathogen virulence are finely tuned by a single variable position contiguous to the catalytic machinery.

García-García A, Hicks T, El Qaidi S, Zhu C, Hardwidge PR, Angulo J, Hurtado-Guerrero R. García-García A, et al. Among authors: hardwidge pr. Chem Sci. 2021 Aug 19;12(36):12181-12191. doi: 10.1039/d1sc04065k. eCollection 2021 Sep 22. Chem Sci. 2021. PMID: 34667584 Free PMC article.

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