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Cancer-Associated Fibroblasts Are Key Determinants of Cancer Cell Invasion in the Earliest Stage of Colorectal Cancer.
Dang H, Harryvan TJ, Liao CY, Danen EHJ, Spalburg VNLN, Kielbasa SM, Mei H, Goeman JJ, de Jonge-Muller ES, Janson SGT, van der Reijden JJ, Crobach S, Hardwick JCH, Boonstra JJ, de Miranda NFCC, Hawinkels LJAC. Dang H, et al. Among authors: hardwick jch. Cell Mol Gastroenterol Hepatol. 2023;16(1):107-131. doi: 10.1016/j.jcmgh.2023.04.004. Epub 2023 Apr 20. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37085135 Free PMC article.
Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.
Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ES, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR. Heijmans J, et al. PLoS One. 2011;6(7):e22620. doi: 10.1371/journal.pone.0022620. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818351 Free PMC article.
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.
Heijmans J, Wielenga MC, Rosekrans SL, van Lidth de Jeude JF, Roelofs J, Groothuis P, Ederveen A, de Jonge-Muller ES, Biemond I, Hardwick JC, D'Haens G, Hommes DW, Muncan V, van den Brink GR. Heijmans J, et al. Gut. 2014 Feb;63(2):310-6. doi: 10.1136/gutjnl-2012-304216. Epub 2013 Feb 13. Gut. 2014. PMID: 23408349
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13. Br J Cancer. 2015. PMID: 25393365 Free PMC article.
100 results