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Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts.
Wright PT, Bhogal NK, Diakonov I, Pannell LMK, Perera RK, Bork NI, Schobesberger S, Lucarelli C, Faggian G, Alvarez-Laviada A, Zaccolo M, Kamp TJ, Balijepalli RC, Lyon AR, Harding SE, Nikolaev VO, Gorelik J. Wright PT, et al. Among authors: harding se. Cell Rep. 2018 Apr 10;23(2):459-469. doi: 10.1016/j.celrep.2018.03.053. Cell Rep. 2018. PMID: 29642004 Free PMC article.
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.
Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J. Wright PT, et al. Among authors: harding se. J Mol Cell Cardiol. 2014 Feb;67:38-48. doi: 10.1016/j.yjmcc.2013.12.003. Epub 2013 Dec 15. J Mol Cell Cardiol. 2014. PMID: 24345421 Free PMC article.
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.
Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. Schobesberger S, et al. Among authors: harding se. Cardiovasc Res. 2017 Jun 1;113(7):770-782. doi: 10.1093/cvr/cvx074. Cardiovasc Res. 2017. PMID: 28505272 Free PMC article.
CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β2AR in isogenic hPSC-derived cardiomyocytes.
Kondrashov A, Mohd Yusof NAN, Hasan A, Goulding J, Kodagoda T, Hoang DM, Vo NTN, Melarangi T, Dolatshad N, Gorelik J, Hill SJ, Harding SE, Denning C. Kondrashov A, et al. Among authors: harding se. Mol Ther Methods Clin Dev. 2020 Oct 27;20:39-53. doi: 10.1016/j.omtm.2020.10.019. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2020. PMID: 33335946 Free PMC article.
496 results