Hardet R - Search Results

1

Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector.

Hardet R, Chevalier B, Dupaty L, Naïmi Y, Riou G, Drouot L, Jean L, Salvetti A, Boyer O, Adriouch S. Hardet R, et al. Mol Ther. 2016 Feb;24(1):87-95. doi: 10.1038/mt.2015.146. Epub 2015 Aug 12. Mol Ther. 2016. PMID: 26265250 Free PMC article.

2

Intrinsic transgene immunogenicity gears CD8(+) T-cell priming after rAAV-mediated muscle gene transfer.

Carpentier M, Lorain S, Chappert P, Lalfer M, Hardet R, Urbain D, Peccate C, Adriouch S, Garcia L, Davoust J, Gross DA. Carpentier M, et al. Among authors: hardet r. Mol Ther. 2015 Apr;23(4):697-706. doi: 10.1038/mt.2014.235. Epub 2014 Dec 10. Mol Ther. 2015. PMID: 25492560 Free PMC article.

3

Evaluation of P2X7 Receptor Function in Tumor Contexts Using rAAV Vector and Nanobodies (AAVnano).

Demeules M, Scarpitta A, Abad C, Gondé H, Hardet R, Pinto-Espinoza C, Eichhoff AM, Schäfer W, Haag F, Koch-Nolte F, Adriouch S. Demeules M, et al. Among authors: hardet r. Front Oncol. 2020 Sep 11;10:1699. doi: 10.3389/fonc.2020.01699. eCollection 2020. Front Oncol. 2020. PMID: 33042812 Free PMC article.

4

Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A.

Long BR, Veron P, Kuranda K, Hardet R, Mitchell N, Hayes GM, Wong WY, Lau K, Li M, Hock MB, Zoog SJ, Vettermann C, Mingozzi F, Schweighardt B. Long BR, et al. Among authors: hardet r. Mol Ther. 2021 Feb 3;29(2):597-610. doi: 10.1016/j.ymthe.2020.12.008. Epub 2020 Dec 10. Mol Ther. 2021. PMID: 33309883 Free PMC article.

5

A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo.

Gondé H, Demeules M, Hardet R, Scarpitta A, Junge M, Pinto-Espinoza C, Varin R, Koch-Nolte F, Boyer O, Adriouch S. Gondé H, et al. Among authors: hardet r. Front Immunol. 2021 Aug 19;12:704408. doi: 10.3389/fimmu.2021.704408. eCollection 2021. Front Immunol. 2021. PMID: 34489954 Free PMC article.

6

Development of Antibody and Nanobody Tools for P2X7.

Stähler T, Danquah W, Demeules M, Gondé H, Hardet R, Haag F, Adriouch S, Koch-Nolte F, Menzel S. Stähler T, et al. Among authors: hardet r. Methods Mol Biol. 2022;2510:99-127. doi: 10.1007/978-1-0716-2384-8_6. Methods Mol Biol. 2022. PMID: 35776322

7

Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo.

Demeules M, Scarpitta A, Hardet R, Gondé H, Abad C, Blandin M, Menzel S, Duan Y, Rissiek B, Magnus T, Mann AM, Koch-Nolte F, Adriouch S. Demeules M, et al. Among authors: hardet r. Front Immunol. 2022 Oct 19;13:1012534. doi: 10.3389/fimmu.2022.1012534. eCollection 2022. Front Immunol. 2022. PMID: 36341324 Free PMC article.

8

Capsid-modified adeno-associated virus vectors as novel vaccine platform for cancer immunotherapy.

Franke AC, Hardet R, Prager L, Bentler M, Demeules M, John-Neek P, Jäschke NM, Ha TC, Hacker UT, Adriouch S, Büning H. Franke AC, et al. Among authors: hardet r. Mol Ther Methods Clin Dev. 2023 Mar 21;29:238-253. doi: 10.1016/j.omtm.2023.03.010. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37090479 Free PMC article.

9

Modifying immune responses to adeno-associated virus vectors by capsid engineering.

Bentler M, Hardet R, Ertelt M, Rudolf D, Kaniowska D, Schneider A, Vondran FWR, Schoeder CT, Delphin M, Lucifora J, Ott M, Hacker UT, Adriouch S, Büning H. Bentler M, et al. Among authors: hardet r. Mol Ther Methods Clin Dev. 2023 Aug 22;30:576-592. doi: 10.1016/j.omtm.2023.08.015. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37693943 Free PMC article.

10

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.

Meliani A, Boisgerault F, Hardet R, Marmier S, Collaud F, Ronzitti G, Leborgne C, Costa Verdera H, Simon Sola M, Charles S, Vignaud A, van Wittenberghe L, Manni G, Christophe O, Fallarino F, Roy C, Michaud A, Ilyinskii P, Kishimoto TK, Mingozzi F. Meliani A, et al. Among authors: hardet r. Nat Commun. 2018 Oct 5;9(1):4098. doi: 10.1038/s41467-018-06621-3. Nat Commun. 2018. PMID: 30291246 Free PMC article.

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