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COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.
Hofmann BT, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak AS, Harder S, El Gammal AT, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki JR, Jücker M, Bockhorn M, Wolters-Eisfeld G. Hofmann BT, et al. Among authors: harder s. Mol Cancer. 2015 May 29;14:109. doi: 10.1186/s12943-015-0386-1. Mol Cancer. 2015. PMID: 26021314 Free PMC article.
Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice.
Wolters-Eisfeld G, Mercanoglu B, Hofmann BT, Wolpers T, Schnabel C, Harder S, Steffen P, Bachmann K, Steglich B, Schrader J, Gagliani N, Schlüter H, Güngör C, Izbicki JR, Wagener C, Bockhorn M. Wolters-Eisfeld G, et al. Among authors: harder s. Exp Mol Med. 2018 Oct 10;50(10):1-13. doi: 10.1038/s12276-018-0157-3. Exp Mol Med. 2018. PMID: 30305605 Free PMC article.
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A. Thürmer M, et al. Among authors: harder s. Nat Commun. 2022 May 27;13(1):2982. doi: 10.1038/s41467-022-30374-9. Nat Commun. 2022. PMID: 35624087 Free PMC article.
506 results