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Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis.
Young L, May B, Pendlebury-Watt A, Shearman J, Elliott C, Albury MS, Shiba T, Inaoka DK, Harada S, Kita K, Moore AL. Young L, et al. Among authors: harada s. Biochim Biophys Acta. 2014 Jul;1837(7):1219-25. doi: 10.1016/j.bbabio.2014.01.027. Epub 2014 Feb 12. Biochim Biophys Acta. 2014. PMID: 24530866 Free article.
Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Shiba T, Inaoka DK, Takahashi G, Tsuge C, Kido Y, Young L, Ueda S, Balogun EO, Nara T, Honma T, Tanaka A, Inoue M, Saimoto H, Harada S, Moore AL, Kita K. Shiba T, et al. Among authors: harada s. Biochim Biophys Acta Bioenerg. 2019 May 1;1860(5):375-382. doi: 10.1016/j.bbabio.2019.03.008. Epub 2019 Mar 22. Biochim Biophys Acta Bioenerg. 2019. PMID: 30910528 Free article.
Structure of the trypanosome cyanide-insensitive alternative oxidase.
Shiba T, Kido Y, Sakamoto K, Inaoka DK, Tsuge C, Tatsumi R, Takahashi G, Balogun EO, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Saimoto H, Moore AL, Harada S, Kita K. Shiba T, et al. Among authors: harada s. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4580-5. doi: 10.1073/pnas.1218386110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487766 Free PMC article.
Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense.
Ebiloma GU, Ayuga TD, Balogun EO, Gil LA, Donachie A, Kaiser M, Herraiz T, Inaoka DK, Shiba T, Harada S, Kita K, de Koning HP, Dardonville C. Ebiloma GU, et al. Among authors: harada s. Eur J Med Chem. 2018 Apr 25;150:385-402. doi: 10.1016/j.ejmech.2018.02.075. Epub 2018 Feb 26. Eur J Med Chem. 2018. PMID: 29544150 Free article.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
Balogun EO, Inaoka DK, Shiba T, Tsuge C, May B, Sato T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PAM, Watanabe YI, Moore AL, Harada S, Kita K. Balogun EO, et al. Among authors: harada s. FASEB J. 2019 Nov;33(11):13002-13013. doi: 10.1096/fj.201901342R. Epub 2019 Sep 16. FASEB J. 2019. PMID: 31525300
., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P. A. M., Watanabe, Y.-I., Moore, A. L., Harada, S., Kita, K. ...
., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P. A. M., Watanabe, Y.-I., Moore, A. L., Harada …
Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei.
Kido Y, Shiba T, Inaoka DK, Sakamoto K, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Moore A, Harada S, Kita K. Kido Y, et al. Among authors: harada s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):275-8. doi: 10.1107/S1744309109054062. Epub 2010 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208159 Free PMC article.
2,096 results