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Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis.
Ko T, Nomura S, Yamada S, Fujita K, Fujita T, Satoh M, Oka C, Katoh M, Ito M, Katagiri M, Sassa T, Zhang B, Hatsuse S, Yamada T, Harada M, Toko H, Amiya E, Hatano M, Kinoshita O, Nawata K, Abe H, Ushiku T, Ono M, Ikeuchi M, Morita H, Aburatani H, Komuro I. Ko T, et al. Among authors: harada m. Nat Commun. 2022 Jun 7;13(1):3275. doi: 10.1038/s41467-022-30630-y. Nat Commun. 2022. PMID: 35672400 Free PMC article.
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.
Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. Sano M, et al. Among authors: harada m. Nature. 2007 Mar 22;446(7134):444-8. doi: 10.1038/nature05602. Epub 2007 Mar 4. Nature. 2007. PMID: 17334357
Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice.
Sun A, Zou Y, Wang P, Xu D, Gong H, Wang S, Qin Y, Zhang P, Chen Y, Harada M, Isse T, Kawamoto T, Fan H, Yang P, Akazawa H, Nagai T, Takano H, Ping P, Komuro I, Ge J. Sun A, et al. Among authors: harada m. J Am Heart Assoc. 2014 Sep 18;3(5):e000779. doi: 10.1161/JAHA.113.000779. J Am Heart Assoc. 2014. PMID: 25237043 Free PMC article.
Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling.
Kumagai H, Ikeda Y, Motozawa Y, Fujishiro M, Okamura T, Fujio K, Okazaki H, Nomura S, Takeda N, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Suzuki J, Yamazaki T, Yamamoto K, Komuro I, Yanagisawa M. Kumagai H, et al. Among authors: harada m. PLoS One. 2015 May 28;10(5):e0129394. doi: 10.1371/journal.pone.0129394. eCollection 2015. PLoS One. 2015. PMID: 26020647 Free PMC article.
Activation of endothelial β-catenin signaling induces heart failure.
Nakagawa A, Naito AT, Sumida T, Nomura S, Shibamoto M, Higo T, Okada K, Sakai T, Hashimoto A, Kuramoto Y, Oka T, Lee JK, Harada M, Ueda K, Shiojima I, Limbourg FP, Adams RH, Noda T, Sakata Y, Akazawa H, Komuro I. Nakagawa A, et al. Among authors: harada m. Sci Rep. 2016 May 5;6:25009. doi: 10.1038/srep25009. Sci Rep. 2016. PMID: 27146149 Free PMC article.
3,862 results