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Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
PLoS Biol. 2021 Apr 22;19(4):e3001191. doi: 10.1371/journal.pbio.3001191. eCollection 2021 Apr.
PLoS Biol. 2021.
PMID: 33886552
Free PMC article.
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
Happ JT, Arveseth CD, Bruystens J, Bertinetti D, Nelson IB, Olivieri C, Zhang J, Hedeen DS, Zhu JF, Capener JL, Bröckel JW, Vu L, King CC, Ruiz-Perez VL, Ge X, Veglia G, Herberg FW, Taylor SS, Myers BR.
Happ JT, et al.
Nat Struct Mol Biol. 2022 Oct;29(10):990-999. doi: 10.1038/s41594-022-00838-z. Epub 2022 Oct 6.
Nat Struct Mol Biol. 2022.
PMID: 36202993
Free PMC article.
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Peroxiredoxin 1 plays a primary role in protecting pancreatic β-cells from hydrogen peroxide and peroxynitrite.
Stancill JS, Happ JT, Broniowska KA, Hogg N, Corbett JA.
Stancill JS, et al. Among authors: happ jt.
Am J Physiol Regul Integr Comp Physiol. 2020 May 1;318(5):R1004-R1013. doi: 10.1152/ajpregu.00011.2020. Epub 2020 Apr 15.
Am J Physiol Regul Integr Comp Physiol. 2020.
PMID: 32292063
Free PMC article.
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