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Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Horgusluoglu E, Neff R, Song WM, Wang M, Wang Q, Arnold M, Krumsiek J, Galindo-Prieto B, Ming C, Nho K, Kastenmüller G, Han X, Baillie R, Zeng Q, Andrews S, Cheng H, Hao K, Goate A, Bennett DA, Saykin AJ, Kaddurah-Daouk R, Zhang B; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Metabolomics Consortium. Horgusluoglu E, et al. Among authors: hao k. Alzheimers Dement. 2022 Jun;18(6):1260-1278. doi: 10.1002/alz.12468. Epub 2021 Nov 10. Alzheimers Dement. 2022. PMID: 34757660 Free PMC article.
Meta-eQTL: a tool set for flexible eQTL meta-analysis.
Di Narzo AF, Cheng H, Lu J, Hao K. Di Narzo AF, et al. Among authors: hao k. BMC Bioinformatics. 2014 Nov 28;15(1):392. doi: 10.1186/s12859-014-0392-0. BMC Bioinformatics. 2014. PMID: 25431350 Free PMC article.
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
Huang KL, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SC, Harari O, Bertelsen S, Fairfax BP, Czajkowski J, Chouraki V, Grenier-Boley B, Bellenguez C, Deming Y, McKenzie A, Raj T, Renton AE, Budde J, Smith A, Fitzpatrick A, Bis JC, DeStefano A, Adams HHH, Ikram MA, van der Lee S, Del-Aguila JL, Fernandez MV, Ibañez L; International Genomics of Alzheimer's Project; Alzheimer's Disease Neuroimaging Initiative; Sims R, Escott-Price V, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Lambert JC, van Duijn C, Launer L, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Zhang B, Borecki I, Kauwe JSK, Cruchaga C, Hao K, Goate AM. Huang KL, et al. Among authors: hao k. Nat Neurosci. 2017 Aug;20(8):1052-1061. doi: 10.1038/nn.4587. Epub 2017 Jun 19. Nat Neurosci. 2017. PMID: 28628103 Free PMC article.
A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. Peters LA, et al. Among authors: hao k. Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038/ng.3947. Epub 2017 Sep 11. Nat Genet. 2017. PMID: 28892060 Free PMC article.
Sex-specific peripheral and central responses to stress-induced depression and treatment in a mouse model.
Deonaraine KK, Wang Q, Cheng H, Chan KL, Lin HY, Liu K, Parise LF, Cathomas F, Leclair KB, Flanigan ME, Li L, Aleyasin H, Guevara C, Hao K, Zhang B, Russo SJ, Wang J. Deonaraine KK, et al. Among authors: hao k. J Neurosci Res. 2020 Dec;98(12):2541-2553. doi: 10.1002/jnr.24724. Epub 2020 Sep 11. J Neurosci Res. 2020. PMID: 32918293 Free PMC article.
846 results