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Complete and long-lasting clinical responses in immune checkpoint inhibitor-resistant, metastasized melanoma treated with adoptive T cell transfer combined with DC vaccination.
Lövgren T, Wolodarski M, Wickström S, Edbäck U, Wallin M, Martell E, Markland K, Blomberg P, Nyström M, Lundqvist A, Jacobsson H, Ullenhag G, Ljungman P, Hansson J, Masucci G, Tell R, Poschke I, Adamson L, Mattsson J, Kiessling R. Lövgren T, et al. Among authors: hansson j. Oncoimmunology. 2020 Jul 11;9(1):1792058. doi: 10.1080/2162402X.2020.1792058. Oncoimmunology. 2020. PMID: 32923156 Free PMC article. Clinical Trial.
Myeloid-derived suppressor cells and their role in CTLA-4 blockade therapy.
Pico de Coaña Y, Masucci G, Hansson J, Kiessling R. Pico de Coaña Y, et al. Among authors: hansson j. Cancer Immunol Immunother. 2014 Sep;63(9):977-83. doi: 10.1007/s00262-014-1570-7. Epub 2014 Jun 26. Cancer Immunol Immunother. 2014. PMID: 24966003 Free PMC article.
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma.
de Coaña YP, Wolodarski M, Poschke I, Yoshimoto Y, Yang Y, Nyström M, Edbäck U, Brage SE, Lundqvist A, Masucci GV, Hansson J, Kiessling R. de Coaña YP, et al. Among authors: hansson j. Oncotarget. 2017 Mar 28;8(13):21539-21553. doi: 10.18632/oncotarget.15368. Oncotarget. 2017. PMID: 28423487 Free PMC article. Clinical Trial.
Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production.
Pico de Coaña Y, Poschke I, Gentilcore G, Mao Y, Nyström M, Hansson J, Masucci GV, Kiessling R. Pico de Coaña Y, et al. Among authors: hansson j. Cancer Immunol Res. 2013 Sep;1(3):158-62. doi: 10.1158/2326-6066.CIR-13-0016. Epub 2013 Aug 2. Cancer Immunol Res. 2013. PMID: 24777678 Clinical Trial.
A phase I clinical trial combining dendritic cell vaccination with adoptive T cell transfer in patients with stage IV melanoma.
Poschke I, Lövgren T, Adamson L, Nyström M, Andersson E, Hansson J, Tell R, Masucci GV, Kiessling R. Poschke I, et al. Among authors: hansson j. Cancer Immunol Immunother. 2014 Oct;63(10):1061-71. doi: 10.1007/s00262-014-1575-2. Epub 2014 Jul 4. Cancer Immunol Immunother. 2014. PMID: 24993563 Free PMC article. Clinical Trial.
471 results