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What Makes a Kinase Promiscuous for Inhibitors?
Hanson SM, Georghiou G, Thakur MK, Miller WT, Rest JS, Chodera JD, Seeliger MA. Hanson SM, et al. Cell Chem Biol. 2019 Mar 21;26(3):390-399.e5. doi: 10.1016/j.chembiol.2018.11.005. Epub 2019 Jan 3. Cell Chem Biol. 2019. PMID: 30612951 Free PMC article.
An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression.
Albanese SK, Parton DL, Işık M, Rodríguez-Laureano L, Hanson SM, Behr JM, Gradia S, Jeans C, Levinson NM, Seeliger MA, Chodera JD. Albanese SK, et al. Among authors: hanson sm. Biochemistry. 2018 Aug 7;57(31):4675-4689. doi: 10.1021/acs.biochem.7b01081. Epub 2018 Jul 26. Biochemistry. 2018. PMID: 30004690 Free PMC article.
Engineering vanilloid-sensitivity into the rat TRPV2 channel.
Zhang F, Hanson SM, Jara-Oseguera A, Krepkiy D, Bae C, Pearce LV, Blumberg PM, Newstead S, Swartz KJ. Zhang F, et al. Among authors: hanson sm. Elife. 2016 May 13;5:e16409. doi: 10.7554/eLife.16409. Elife. 2016. PMID: 27177419 Free PMC article.
Heat activation is intrinsic to the pore domain of TRPV1.
Zhang F, Jara-Oseguera A, Chang TH, Bae C, Hanson SM, Swartz KJ. Zhang F, et al. Among authors: hanson sm. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E317-E324. doi: 10.1073/pnas.1717192115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279388 Free PMC article.
Specificity, synergy, and mechanisms of splice-modifying drugs.
Ishigami Y, Wong MS, Martí-Gómez C, Ayaz A, Kooshkbaghi M, Hanson SM, McCandlish DM, Krainer AR, Kinney JB. Ishigami Y, et al. Among authors: hanson sm. Nat Commun. 2024 Feb 29;15(1):1880. doi: 10.1038/s41467-024-46090-5. Nat Commun. 2024. PMID: 38424098 Free PMC article.
79 results