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What can mathematical modelling say about CHO metabolism and protein glycosylation?
Galleguillos SN, Ruckerbauer D, Gerstl MP, Borth N, Hanscho M, Zanghellini J. Galleguillos SN, et al. Among authors: hanscho m. Comput Struct Biotechnol J. 2017 Jan 28;15:212-221. doi: 10.1016/j.csbj.2017.01.005. eCollection 2017. Comput Struct Biotechnol J. 2017. PMID: 28228925 Free PMC article. Review.
What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines.
Széliová D, Ruckerbauer DE, Galleguillos SN, Petersen LB, Natter K, Hanscho M, Troyer C, Causon T, Schoeny H, Christensen HB, Lee DY, Lewis NE, Koellensperger G, Hann S, Nielsen LK, Borth N, Zanghellini J. Széliová D, et al. Among authors: hanscho m. Metab Eng. 2020 Sep;61:288-300. doi: 10.1016/j.ymben.2020.06.002. Epub 2020 Jun 30. Metab Eng. 2020. PMID: 32619503 Free article.
Inclusion of maintenance energy improves the intracellular flux predictions of CHO.
Széliová D, Štor J, Thiel I, Weinguny M, Hanscho M, Lhota G, Borth N, Zanghellini J, Ruckerbauer DE, Rocha I. Széliová D, et al. Among authors: hanscho m. PLoS Comput Biol. 2021 Jun 11;17(6):e1009022. doi: 10.1371/journal.pcbi.1009022. eCollection 2021 Jun. PLoS Comput Biol. 2021. PMID: 34115746 Free PMC article.
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.
Feichtinger J, Hernández I, Fischer C, Hanscho M, Auer N, Hackl M, Jadhav V, Baumann M, Krempl PM, Schmidl C, Farlik M, Schuster M, Merkel A, Sommer A, Heath S, Rico D, Bock C, Thallinger GG, Borth N. Feichtinger J, et al. Among authors: hanscho m. Biotechnol Bioeng. 2016 Oct;113(10):2241-53. doi: 10.1002/bit.25990. Epub 2016 Apr 29. Biotechnol Bioeng. 2016. PMID: 27072894 Free PMC article.
16 results