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Page 1
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Among authors: van dam h. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744
Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.
Gan J, de Vries J, Akkermans JJLL, Mohammed Y, Tjokrodirijo RTN, de Ru AH, Kim RQ, Vargas DA, Pol V, Fasan R, van Veelen PA, Neefjes J, van Dam H, Ovaa H, Sapmaz A, Geurink PP. Gan J, et al. Among authors: van dam h. ACS Chem Biol. 2023 Sep 15;18(9):2003-2013. doi: 10.1021/acschembio.3c00227. Epub 2023 Aug 29. ACS Chem Biol. 2023. PMID: 37642399 Free PMC article.
A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity.
Pérez Berrocal DA, Vishwanatha TM, Horn-Ghetko D, Botsch JJ, Hehl LA, Kostrhon S, Misra M, Ðikić I, Geurink PP, van Dam H, Schulman BA, Mulder MPC. Pérez Berrocal DA, et al. Among authors: van dam h. Angew Chem Int Ed Engl. 2023 Aug 7;62(32):e202303319. doi: 10.1002/anie.202303319. Epub 2023 Jun 27. Angew Chem Int Ed Engl. 2023. PMID: 37272691
OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.
Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L. Zhang Z, et al. Among authors: van dam h. Mol Cell. 2019 Jan 3;73(1):7-21.e7. doi: 10.1016/j.molcel.2018.10.030. Epub 2018 Nov 21. Mol Cell. 2019. PMID: 30472188 Free article.
51 results