Hannun YA - Search Results

1

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation.

Boyd RA, Majumder S, Stiban J, Mavodza G, Straus AJ, Kempelingaiah SK, Reddy V, Hannun YA, Obeid LM, Senkal CE. Boyd RA, et al. Among authors: hannun ya. Cell Rep. 2023 Sep 26;42(9):113081. doi: 10.1016/j.celrep.2023.113081. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37689067 Free PMC article.

2

Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail.

Bonica J, Clarke CJ, Obeid LM, Luberto C, Hannun YA. Bonica J, et al. Among authors: hannun ya. FASEB J. 2023 Mar;37(3):e22787. doi: 10.1096/fj.202201066R. FASEB J. 2023. PMID: 36723905 Free PMC article.

3

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding.

Al-Rashed F, Haddad D, Al Madhoun A, Sindhu S, Jacob T, Kochumon S, Obeid LM, Al-Mulla F, Hannun YA, Ahmad R. Al-Rashed F, et al. Among authors: hannun ya. iScience. 2023 Jun 15;26(7):107145. doi: 10.1016/j.isci.2023.107145. eCollection 2023 Jul 21. iScience. 2023. PMID: 37416456 Free PMC article.

4

A novel HSPB1^S139F mouse model of Charcot-Marie-Tooth Disease.

Espinoza KS, Hermanson KN, Beard CA, Schwartz NU, Snider JM, Low BE, Wiles MV, Hannun YA, Obeid LM, Snider AJ. Espinoza KS, et al. Among authors: hannun ya. Prostaglandins Other Lipid Mediat. 2023 Dec;169:106769. doi: 10.1016/j.prostaglandins.2023.106769. Epub 2023 Aug 23. Prostaglandins Other Lipid Mediat. 2023. PMID: 37625781

5

Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and Disease.

Richardson WJ, Humphrey SB, Sears SM, Hoffman NA, Orwick AJ, Doll MA, Doll CL, Xia C, Hernandez-Corbacho M, Snider JM, Obeid LM, Hannun YA, Snider AJ, Siskind LJ. Richardson WJ, et al. Among authors: hannun ya. Mol Pharmacol. 2024 Feb 15;105(3):131-143. doi: 10.1124/molpharm.123.000788. Mol Pharmacol. 2024. PMID: 38164625 Free PMC article.

6

Biological function, topology, and quantification of plasma membrane Ceramide.

Canals D, Hannun YA. Canals D, et al. Among authors: hannun ya. Adv Biol Regul. 2024 Jan;91:101009. doi: 10.1016/j.jbior.2023.101009. Epub 2023 Dec 14. Adv Biol Regul. 2024. PMID: 38128364 Review.

7

A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane.

Greene M, Hernandez-Corbacho MJ, Ostermeyer-Fay AG, Hannun YA, Canals D. Greene M, et al. Among authors: hannun ya. J Lipid Res. 2023 Feb;64(2):100322. doi: 10.1016/j.jlr.2022.100322. Epub 2022 Dec 20. J Lipid Res. 2023. PMID: 36549592 Free PMC article.

8

A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process.

Liao R, Babatunde A, Qiu S, Harikumar H, Coon JJ, Overmyer KA, Hannun YA, Luberto C, Bresnick EH. Liao R, et al. Among authors: hannun ya. Nat Commun. 2023 Nov 9;14(1):7262. doi: 10.1038/s41467-023-42978-w. Nat Commun. 2023. PMID: 37945603 Free PMC article.

9

Neutral ceramidase-active site inhibitor chemotypes and binding modes.

Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Among authors: hannun ya. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.

10

Targeting acid ceramidase ameliorates fibrosis in mouse models of non-alcoholic steatohepatitis.

Yu A, Cable C, Sharma S, Shihan MH, Mattis AN, Mileva I, Hannun YA, Duwaerts CC, Chen JY. Yu A, et al. Among authors: hannun ya. Front Med (Lausanne). 2022 Oct 6;9:881848. doi: 10.3389/fmed.2022.881848. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36275798 Free PMC article.

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