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Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A.
Naganawa M, Gallezot JD, Finnema SJ, Maguire RP, Mercier J, Nabulsi NB, Kervyn S, Henry S, Nicolas JM, Huang Y, Chen MK, Hannestad J, Klitgaard H, Stockis A, Carson RE. Naganawa M, et al. Among authors: hannestad j. EJNMMI Res. 2022 Nov 8;12(1):71. doi: 10.1186/s13550-022-00944-5. EJNMMI Res. 2022. PMID: 36346513 Free PMC article.
Safety and tolerability of GRF6019 in mild-to-moderate Alzheimer's disease dementia.
Hannestad J, Koborsi K, Klutzaritz V, Chao W, Ray R, Páez A, Jackson S, Lohr S, Cummings JL, Kay G, Nikolich K, Braithwaite S. Hannestad J, et al. Alzheimers Dement (N Y). 2020 Dec 16;6(1):e12115. doi: 10.1002/trc2.12115. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 33344754 Free PMC article.
Padsevonil randomized Phase IIa trial in treatment-resistant focal epilepsy: a translational approach.
Muglia P, Hannestad J, Brandt C, DeBruyn S, Germani M, Lacroix B, Majoie M, Otoul C, Sciberras D, Steinhoff BJ, Van Laere K, Van Paesschen W, Webster E, Kaminski RM, Werhahn KJ, Toledo M. Muglia P, et al. Among authors: hannestad j. Brain Commun. 2020 Nov 2;2(2):fcaa183. doi: 10.1093/braincomms/fcaa183. eCollection 2020. Brain Commun. 2020. PMID: 33241213 Free PMC article.
A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers.
Finnema SJ, Rossano S, Naganawa M, Henry S, Gao H, Pracitto R, Maguire RP, Mercier J, Kervyn S, Nicolas JM, Klitgaard H, DeBruyn S, Otoul C, Martin P, Muglia P, Matuskey D, Nabulsi NB, Huang Y, Kaminski RM, Hannestad J, Stockis A, Carson RE. Finnema SJ, et al. Among authors: hannestad j. Epilepsia. 2019 May;60(5):958-967. doi: 10.1111/epi.14701. Epub 2019 Mar 29. Epilepsia. 2019. PMID: 30924924 Free PMC article. Clinical Trial.
77 results