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Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Custódio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hällberg BM, Löw C. Custódio TF, et al. Among authors: hanke l. Nat Commun. 2020 Nov 4;11(1):5588. doi: 10.1038/s41467-020-19204-y. Nat Commun. 2020. PMID: 33149112 Free PMC article.
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Hanke L, Vidakovics Perez L, Sheward DJ, Das H, Schulte T, Moliner-Morro A, Corcoran M, Achour A, Karlsson Hedestam GB, Hällberg BM, Murrell B, McInerney GM. Hanke L, et al. Nat Commun. 2020 Sep 4;11(1):4420. doi: 10.1038/s41467-020-18174-5. Nat Commun. 2020. PMID: 32887876 Free PMC article.
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.
Rudberg AS, Havervall S, Månberg A, Jernbom Falk A, Aguilera K, Ng H, Gabrielsson L, Salomonsson AC, Hanke L, Murrell B, McInerney G, Olofsson J, Andersson E, Hellström C, Bayati S, Bergström S, Pin E, Sjöberg R, Tegel H, Hedhammar M, Phillipson M, Nilsson P, Hober S, Thålin C. Rudberg AS, et al. Among authors: hanke l. Nat Commun. 2020 Oct 8;11(1):5064. doi: 10.1038/s41467-020-18848-0. Nat Commun. 2020. PMID: 33033249 Free PMC article.
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Koenig PA, Das H, Liu H, Kümmerer BM, Gohr FN, Jenster LM, Schiffelers LDJ, Tesfamariam YM, Uchima M, Wuerth JD, Gatterdam K, Ruetalo N, Christensen MH, Fandrey CI, Normann S, Tödtmann JMP, Pritzl S, Hanke L, Boos J, Yuan M, Zhu X, Schmid-Burgk JL, Kato H, Schindler M, Wilson IA, Geyer M, Ludwig KU, Hällberg BM, Wu NC, Schmidt FI. Koenig PA, et al. Among authors: hanke l. Science. 2021 Feb 12;371(6530):eabe6230. doi: 10.1126/science.abe6230. Epub 2021 Jan 12. Science. 2021. PMID: 33436526 Free PMC article.
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses.
Mandolesi M, Sheward DJ, Hanke L, Ma J, Pushparaj P, Perez Vidakovics L, Kim C, Àdori M, Lenart K, Loré K, Castro Dopico X, Coquet JM, McInerney GM, Karlsson Hedestam GB, Murrell B. Mandolesi M, et al. Among authors: hanke l. Cell Rep Med. 2021 Apr 20;2(4):100252. doi: 10.1016/j.xcrm.2021.100252. Epub 2021 Apr 5. Cell Rep Med. 2021. PMID: 33842900 Free PMC article.
Seropositivity in blood donors and pregnant women during the first year of SARS-CoV-2 transmission in Stockholm, Sweden.
Castro Dopico X, Muschiol S, Christian M, Hanke L, Sheward DJ, Grinberg NF, Rorbach J, Bogdanovic G, Mcinerney GM, Allander T, Wallace C, Murrell B, Albert J, Karlsson Hedestam GB. Castro Dopico X, et al. Among authors: hanke l. J Intern Med. 2021 Sep;290(3):666-676. doi: 10.1111/joim.13304. Epub 2021 May 18. J Intern Med. 2021. PMID: 34008203 Free PMC article.
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, Mattsson C, Hanke L, Dodig-Crnković T, Christian M, Meineke B, Elsässer S, Andréll J, Havervall S, Thålin C, Eklund C, Dillner J, Beck O, Thomas CE, McInerney G, Hong MG, Murrell B, Fredolini C, Schwenk JM. Roxhed N, et al. Among authors: hanke l. Nat Commun. 2021 Jun 17;12(1):3695. doi: 10.1038/s41467-021-23893-4. Nat Commun. 2021. PMID: 34140485 Free PMC article.
53 results