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Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch.
Balzulat A, Zhu WF, Flauaus C, Hernandez-Olmos V, Heering J, Sethumadhavan S, Dubiel M, Frank A, Menge A, Hebchen M, Metzner K, Lu R, Lukowski R, Ruth P, Knapp S, Müller S, Steinhilber D, Hänelt I, Stark H, Proschak E, Schmidtko A. Balzulat A, et al. Among authors: hanelt i. Adv Sci (Weinh). 2024 Apr;11(15):e2307237. doi: 10.1002/advs.202307237. Epub 2024 Feb 13. Adv Sci (Weinh). 2024. PMID: 38350720 Free PMC article.
Understanding the cell: Future views of structural biology.
Beck M, Covino R, Hänelt I, Müller-McNicoll M. Beck M, et al. Among authors: hanelt i. Cell. 2024 Feb 1;187(3):545-562. doi: 10.1016/j.cell.2023.12.017. Cell. 2024. PMID: 38306981 Free article. Review.
Inhibited KdpFABC transitions into an E1 off-cycle state.
Silberberg JM, Stock C, Hielkema L, Corey RA, Rheinberger J, Wunnicke D, Dubach VRA, Stansfeld PJ, Hänelt I, Paulino C. Silberberg JM, et al. Among authors: hanelt i. Elife. 2022 Oct 18;11:e80988. doi: 10.7554/eLife.80988. Elife. 2022. PMID: 36255052 Free PMC article.
Molecular Mechanisms for Bacterial Potassium Homeostasis.
Stautz J, Hellmich Y, Fuss MF, Silberberg JM, Devlin JR, Stockbridge RB, Hänelt I. Stautz J, et al. Among authors: hanelt i. J Mol Biol. 2021 Aug 6;433(16):166968. doi: 10.1016/j.jmb.2021.166968. Epub 2021 Mar 30. J Mol Biol. 2021. PMID: 33798529 Free PMC article. Review.
Regulation of lipid saturation without sensing membrane fluidity.
Ballweg S, Sezgin E, Doktorova M, Covino R, Reinhard J, Wunnicke D, Hänelt I, Levental I, Hummer G, Ernst R. Ballweg S, et al. Among authors: hanelt i. Nat Commun. 2020 Feb 6;11(1):756. doi: 10.1038/s41467-020-14528-1. Nat Commun. 2020. PMID: 32029718 Free PMC article.
32 results