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A nitroalkene derivative of salicylate alleviates diet-induced obesity by activating creatine metabolism and non-shivering thermogenesis.
Cal K, Leyva A, Rodríguez-Duarte J, Ruiz S, Santos L, Colella L, Ingold M, Vilaseca C, Galliussi G, Ziegler L, Peclat TR, Bresque M, Handy RM, King R, Dos Reis LM, Espasandin C, Breining P, Dapueto R, Lopez A, Thompson KL, Agorrody G, DeVallance E, Meadows E, Lewis SE, Barbosa GCS, de Souza LOL, Chichierchio MS, Valez V, Aicardo A, Contreras P, Vendelbo MH, Jakobsen S, Kamaid A, Porcal W, Calliari A, Verdes JM, Du J, Wang Y, Hollander JM, White TA, Radi R, Moyna G, Quijano C, O'Doherty R, Moraes-Vieira P, Holloway GP, Leonardi R, Mori MA, Camacho-Pereira J, Kelley EE, Duran R, Lopez GV, Batthyány C, Chini EN, Escande C. Cal K, et al. Among authors: handy rm. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-3101395. doi: 10.21203/rs.3.rs-3101395/v1. Res Sq. 2023. PMID: 37502859 Free PMC article. Preprint.
Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
Petrick HL, Ogilvie LM, Brunetta HS, Robinson A, Kirsh AJ, Barbeau PA, Handy RM, Coyle-Asbil B, Gianetto-Hill C, Dennis KMJH, van Loon LJC, Chabowski A, Schertzer JD, Allen-Vercoe E, Simpson JA, Holloway GP. Petrick HL, et al. Among authors: handy rm. Diabetes. 2023 Jul 1;72(7):844-856. doi: 10.2337/db22-0575. Diabetes. 2023. PMID: 36812497