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α-hemolysin of Staphylococcus aureus impairs thrombus formation.
Jahn K, Handtke S, Palankar R, Kohler TP, Wesche J, Wolff M, Bayer J, Wolz C, Greinacher A, Hammerschmidt S. Jahn K, et al. Among authors: handtke s. J Thromb Haemost. 2022 Jun;20(6):1464-1475. doi: 10.1111/jth.15703. Epub 2022 Mar 27. J Thromb Haemost. 2022. PMID: 35303391 Free article.
Polyvalent Immunoglobulin Preparations Inhibit Pneumolysin-Induced Platelet Destruction.
Wiebe F, Handtke S, Wesche J, Schnarre A, Palankar R, Wolff M, Jahn K, Voß F, Weißmüller S, Schüttrumpf J, Greinacher A, Hammerschmidt S. Wiebe F, et al. Among authors: handtke s. Thromb Haemost. 2022 Jul;122(7):1147-1158. doi: 10.1055/a-1723-1880. Epub 2021 Dec 16. Thromb Haemost. 2022. PMID: 34918314 Free PMC article.
Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro.
Jahn K, Handtke S, Palankar R, Weißmüller S, Nouailles G, Kohler TP, Wesche J, Rohde M, Heinz C, Aschenbrenner AF, Wolff M, Schüttrumpf J, Witzenrath M, Hammerschmidt S, Greinacher A. Jahn K, et al. Among authors: handtke s. Blood Adv. 2020 Dec 22;4(24):6315-6326. doi: 10.1182/bloodadvances.2020002372. Blood Adv. 2020. PMID: 33351126 Free PMC article. Clinical Trial.
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia.
Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T. Greinacher A, et al. Among authors: handtke s. Blood. 2021 Dec 2;138(22):2256-2268. doi: 10.1182/blood.2021013231. Blood. 2021. PMID: 34587242 Free PMC article.
Pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT).
Greinacher A, Schönborn L, Siegerist F, Steil L, Palankar R, Handtke S, Reder A, Thiele T, Aurich K, Methling K, Lalk M, Völker U, Endlich N. Greinacher A, et al. Among authors: handtke s. Semin Hematol. 2022 Apr;59(2):97-107. doi: 10.1053/j.seminhematol.2022.02.004. Epub 2022 Feb 23. Semin Hematol. 2022. PMID: 35512907 Free PMC article.
21 results