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The biology of PGC-1α and its therapeutic potential.
Handschin C. Handschin C. Trends Pharmacol Sci. 2009 Jun;30(6):322-9. doi: 10.1016/j.tips.2009.03.006. Epub 2009 May 14. Trends Pharmacol Sci. 2009. PMID: 19446346 Free article. Review.
PGC-1α and myokines in the aging muscle - a mini-review.
Arnold AS, Egger A, Handschin C. Arnold AS, et al. Among authors: handschin c. Gerontology. 2011;57(1):37-43. doi: 10.1159/000281883. Epub 2010 Feb 4. Gerontology. 2011. PMID: 20134150 Free article. Review.
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.
Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C. Summermatter S, et al. Among authors: handschin c. J Biol Chem. 2010 Oct 22;285(43):32793-32800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17. J Biol Chem. 2010. PMID: 20716531 Free PMC article.
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA. Romanino K, et al. Among authors: handschin c. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20808-13. doi: 10.1073/pnas.1111448109. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143799 Free PMC article.
153 results