Hancock SM - Search Results

1

Engineering of glycosidases and glycosyltransferases.

Hancock SM, Vaughan MD, Withers SG. Hancock SM, et al. Curr Opin Chem Biol. 2006 Oct;10(5):509-19. doi: 10.1016/j.cbpa.2006.07.015. Epub 2006 Aug 14. Curr Opin Chem Biol. 2006. PMID: 16905354 Review.

2

Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms.

Caines ME, Vaughan MD, Tarling CA, Hancock SM, Warren RA, Withers SG, Strynadka NC. Caines ME, et al. Among authors: hancock sm. J Biol Chem. 2007 May 11;282(19):14300-8. doi: 10.1074/jbc.M611455200. Epub 2007 Feb 28. J Biol Chem. 2007. PMID: 17329247 Free article.

3

Designer enzymes for glycosphingolipid synthesis by directed evolution.

Hancock SM, Rich JR, Caines ME, Strynadka NC, Withers SG. Hancock SM, et al. Nat Chem Biol. 2009 Jul;5(7):508-14. doi: 10.1038/nchembio.191. Nat Chem Biol. 2009. PMID: 19525967

4

The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.

Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stütz AE, Vasella A, Withers SG, Strynadka NC. Caines ME, et al. Among authors: hancock sm. Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268. Angew Chem Int Ed Engl. 2007. PMID: 17487923 No abstract available.

5

High-throughput screening of cell lysates for ganglioside synthesis.

Hancock SM, Tarling CA, Withers SG. Hancock SM, et al. Anal Biochem. 2008 Nov 1;382(1):48-54. doi: 10.1016/j.ab.2008.07.023. Epub 2008 Jul 29. Anal Biochem. 2008. PMID: 18703011

6

Self-immobilizing fluorogenic imaging agents of enzyme activity.

Kwan DH, Chen HM, Ratananikom K, Hancock SM, Watanabe Y, Kongsaeree PT, Samuels AL, Withers SG. Kwan DH, et al. Among authors: hancock sm. Angew Chem Int Ed Engl. 2011 Jan 3;50(1):300-3. doi: 10.1002/anie.201005705. Angew Chem Int Ed Engl. 2011. PMID: 21184404 No abstract available.

7

Developing promiscuous glycosidases for glycoside synthesis: residues W433 and E432 in Sulfolobus solfataricus beta-glycosidase are important glucoside- and galactoside-specificity determinants.

Hancock SM, Corbett K, Fordham-Skelton AP, Gatehouse JA, Davis BG. Hancock SM, et al. Chembiochem. 2005 May;6(5):866-75. doi: 10.1002/cbic.200400341. Chembiochem. 2005. PMID: 15846595

8

A front-face 'S_Ni synthase' engineered from a retaining 'double-S_N2' hydrolase.

Iglesias-Fernández J, Hancock SM, Lee SS, Khan M, Kirkpatrick J, Oldham NJ, McAuley K, Fordham-Skelton A, Rovira C, Davis BG. Iglesias-Fernández J, et al. Among authors: hancock sm. Nat Chem Biol. 2017 Aug;13(8):874-881. doi: 10.1038/nchembio.2394. Epub 2017 Jun 12. Nat Chem Biol. 2017. PMID: 28604696

9

Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog.

Rogerson DT, Sachdeva A, Wang K, Haq T, Kazlauskaite A, Hancock SM, Huguenin-Dezot N, Muqit MM, Fry AM, Bayliss R, Chin JW. Rogerson DT, et al. Among authors: hancock sm. Nat Chem Biol. 2015 Jul;11(7):496-503. doi: 10.1038/nchembio.1823. Epub 2015 Jun 1. Nat Chem Biol. 2015. PMID: 26030730 Free PMC article.

10

Genetic encoding of photocaged cysteine allows photoactivation of TEV protease in live mammalian cells.

Nguyen DP, Mahesh M, Elsässer SJ, Hancock SM, Uttamapinant C, Chin JW. Nguyen DP, et al. Among authors: hancock sm. J Am Chem Soc. 2014 Feb 12;136(6):2240-3. doi: 10.1021/ja412191m. Epub 2014 Jan 30. J Am Chem Soc. 2014. PMID: 24479649 Free PMC article.

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