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Page 1
Reimagine fire science for the anthropocene.
Shuman JK, Balch JK, Barnes RT, Higuera PE, Roos CI, Schwilk DW, Stavros EN, Banerjee T, Bela MM, Bendix J, Bertolino S, Bililign S, Bladon KD, Brando P, Breidenthal RE, Buma B, Calhoun D, Carvalho LMV, Cattau ME, Cawley KM, Chandra S, Chipman ML, Cobian-Iñiguez J, Conlisk E, Coop JD, Cullen A, Davis KT, Dayalu A, De Sales F, Dolman M, Ellsworth LM, Franklin S, Guiterman CH, Hamilton M, Hanan EJ, Hansen WD, Hantson S, Harvey BJ, Holz A, Huang T, Hurteau MD, Ilangakoon NT, Jennings M, Jones C, Klimaszewski-Patterson A, Kobziar LN, Kominoski J, Kosovic B, Krawchuk MA, Laris P, Leonard J, Loria-Salazar SM, Lucash M, Mahmoud H, Margolis E, Maxwell T, McCarty JL, McWethy DB, Meyer RS, Miesel JR, Moser WK, Nagy RC, Niyogi D, Palmer HM, Pellegrini A, Poulter B, Robertson K, Rocha AV, Sadegh M, Santos F, Scordo F, Sexton JO, Sharma AS, Smith AMS, Soja AJ, Still C, Swetnam T, Syphard AD, Tingley MW, Tohidi A, Trugman AT, Turetsky M, Varner JM, Wang Y, Whitman T, Yelenik S, Zhang X. Shuman JK, et al. Among authors: hanan ej. PNAS Nexus. 2022 Aug 4;1(3):pgac115. doi: 10.1093/pnasnexus/pgac115. eCollection 2022 Jul. PNAS Nexus. 2022. PMID: 36741468 Free PMC article.
Lipid Tales: Optimizing Arylomycin Membrane Anchors.
Koehler MFT, Chen YC, Chen Y, Chen Y, Crawford JJ, Durk MR, Garland K, Hanan EJ, Higuchi RI, Hu H, Ly CQ, Paraselli PG, Roberts TC, Schwarz JB, Smith PA, Yu Z, Heise CE. Koehler MFT, et al. Among authors: hanan ej. ACS Med Chem Lett. 2023 Oct 11;14(11):1524-1530. doi: 10.1021/acsmedchemlett.3c00327. eCollection 2023 Nov 9. ACS Med Chem Lett. 2023. PMID: 37974942
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.
Song KW, Edgar KA, Hanan EJ, Hafner M, Oeh J, Merchant M, Sampath D, Nannini MA, Hong R, Phu L, Forrest WF, Stawiski E, Schmidt S, Endres N, Guan J, Wallin JJ, Cheong J, Plise EG, Lewis Phillips GD, Salphati L, Heffron TP, Olivero AG, Malek S, Staben ST, Kirkpatrick DS, Dey A, Friedman LS. Song KW, et al. Among authors: hanan ej. Cancer Discov. 2022 Jan;12(1):204-219. doi: 10.1158/2159-8290.CD-21-0072. Epub 2021 Sep 20. Cancer Discov. 2022. PMID: 34544753 Free PMC article.
Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal Peptidase.
Pantua H, Skippington E, Braun MG, Noland CL, Diao J, Peng Y, Gloor SL, Yan D, Kang J, Katakam AK, Reeder J, Castanedo GM, Garland K, Komuves L, Sagolla M, Austin CD, Murray J, Xu Y, Modrusan Z, Xu M, Hanan EJ, Kapadia SB. Pantua H, et al. Among authors: hanan ej. mBio. 2020 Sep 8;11(5):e02018-20. doi: 10.1128/mBio.02018-20. mBio. 2020. PMID: 32900806 Free PMC article.
Structure of the essential inner membrane lipopolysaccharide-PbgA complex.
Clairfeuille T, Buchholz KR, Li Q, Verschueren E, Liu P, Sangaraju D, Park S, Noland CL, Storek KM, Nickerson NN, Martin L, Dela Vega T, Miu A, Reeder J, Ruiz-Gonzalez M, Swem D, Han G, DePonte DP, Hunter MS, Gati C, Shahidi-Latham S, Xu M, Skelton N, Sellers BD, Skippington E, Sandoval W, Hanan EJ, Payandeh J, Rutherford ST. Clairfeuille T, et al. Among authors: hanan ej. Nature. 2020 Aug;584(7821):479-483. doi: 10.1038/s41586-020-2597-x. Epub 2020 Aug 12. Nature. 2020. PMID: 32788728
29 results