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Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development.
Vanova T, Sedmik J, Raska J, Amruz Cerna K, Taus P, Pospisilova V, Nezvedova M, Fedorova V, Kadakova S, Klimova H, Capandova M, Orviska P, Fojtik P, Bartova S, Plevova K, Spacil Z, Hribkova H, Bohaciakova D. Vanova T, et al. Among authors: hribkova h. Cell Rep. 2023 Nov 28;42(11):113310. doi: 10.1016/j.celrep.2023.113310. Epub 2023 Oct 20. Cell Rep. 2023. PMID: 37864790 Free article.
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Nemergut M, Marques SM, Uhrik L, Vanova T, Nezvedova M, Gadara DC, Jha D, Tulis J, Novakova V, Planas-Iglesias J, Kunka A, Legrand A, Hribkova H, Pospisilova V, Sedmik J, Raska J, Prokop Z, Damborsky J, Bohaciakova D, Spacil Z, Hernychova L, Bednar D, Marek M. Nemergut M, et al. Among authors: hribkova h. Mol Neurodegener. 2023 Jun 6;18(1):38. doi: 10.1186/s13024-023-00620-9. Mol Neurodegener. 2023. PMID: 37280636 Free PMC article.
Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds.
Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S. Palušová V, et al. Among authors: hribkova h. Cancers (Basel). 2020 Jun 10;12(6):1516. doi: 10.3390/cancers12061516. Cancers (Basel). 2020. PMID: 32531927 Free PMC article.
Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of secondary neurulation.
Fedorova V, Vanova T, Elrefae L, Pospisil J, Petrasova M, Kolajova V, Hudacova Z, Baniariova J, Barak M, Peskova L, Barta T, Kaucka M, Killinger M, Vecera J, Bernatik O, Cajanek L, Hribkova H, Bohaciakova D. Fedorova V, et al. Among authors: hribkova h. Stem Cell Res. 2019 Oct;40:101563. doi: 10.1016/j.scr.2019.101563. Epub 2019 Aug 29. Stem Cell Res. 2019. PMID: 31494448 Free article.
15 results