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Klotho inhibits PKCα/p66SHC-mediated podocyte injury in diabetic nephropathy.
Jiang W, Xiao T, Han W, Xiong J, He T, Liu Y, Huang Y, Yang K, Bi X, Xu X, Yu Y, Li Y, Gu J, Zhang J, Huang Y, Zhang B, Zhao J. Jiang W, et al. Among authors: han w. Mol Cell Endocrinol. 2019 Aug 20;494:110490. doi: 10.1016/j.mce.2019.110490. Epub 2019 Jun 14. Mol Cell Endocrinol. 2019. PMID: 31207271
IRF-1 promotes renal fibrosis by downregulation of Klotho.
Li Y, Liu Y, Huang Y, Yang K, Xiao T, Xiong J, Wang K, Liu C, He T, Yu Y, Han W, Wang Y, Bi X, Zhang J, Huang Y, Zhang B, Zhao J. Li Y, et al. Among authors: han w. FASEB J. 2020 Mar;34(3):4415-4429. doi: 10.1096/fj.201902446R. Epub 2020 Jan 21. FASEB J. 2020. PMID: 31965641
IRF1-mediated downregulation of PGC1α contributes to cardiorenal syndrome type 4.
Huang Y, Wang S, Zhou J, Liu Y, Du C, Yang K, Bi X, Liu M, Han W, Wang K, Xiong J, Wang S, Wang Y, Nie L, Liu C, Zhang D, Gu J, Zeng C, Zhao J. Huang Y, et al. Among authors: han w. Nat Commun. 2020 Sep 16;11(1):4664. doi: 10.1038/s41467-020-18519-0. Nat Commun. 2020. PMID: 32938919 Free PMC article.
Mitochondrial Damage-Induced Innate Immune Activation in Vascular Smooth Muscle Cells Promotes Chronic Kidney Disease-Associated Plaque Vulnerability.
Bi X, Du C, Wang X, Wang XY, Han W, Wang Y, Qiao Y, Zhu Y, Ran L, Liu Y, Xiong J, Huang Y, Liu M, Liu C, Zeng C, Wang J, Yang K, Zhao J. Bi X, et al. Among authors: han w. Adv Sci (Weinh). 2021 Jan 6;8(5):2002738. doi: 10.1002/advs.202002738. eCollection 2021 Mar. Adv Sci (Weinh). 2021. PMID: 33717842 Free PMC article.
8,098 results