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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. Yamamoto J, et al. Among authors: han q. iScience. 2022 Mar 25;25(4):104162. doi: 10.1016/j.isci.2022.104162. eCollection 2022 Apr 15. iScience. 2022. PMID: 35434545 Free PMC article.
Homogeneous enzymatic colorimetric assay for total cysteine.
Han Q, Xu M, Tang L, Sun X, Zhang N, Tan X, Tan X, Tan Y, Hoffman RM. Han Q, et al. Clin Chem. 2004 Jul;50(7):1229-31. doi: 10.1373/clinchem.2004.032920. Clin Chem. 2004. PMID: 15229150 No abstract available.
Enzymatic assay for total plasma Cys.
Han Q, Hoffman RM. Han Q, et al. Nat Protoc. 2008;3(11):1778-81. doi: 10.1038/nprot.2008.178. Nat Protoc. 2008. PMID: 18948977
Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging.
Yano S, Takehara K, Zhao M, Tan Y, Han Q, Li S, Bouvet M, Fujiwara T, Hoffman RM. Yano S, et al. Among authors: han q. Cell Cycle. 2016 Jul 2;15(13):1715-23. doi: 10.1080/15384101.2016.1181240. Epub 2016 May 6. Cell Cycle. 2016. PMID: 27152859 Free PMC article.
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Murakami T, Li S, Han Q, Tan Y, Kiyuna T, Igarashi K, Kawaguchi K, Hwang HK, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Hiroshima Y, Lwin TM, DeLong JC, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: han q. Oncotarget. 2017 May 30;8(22):35630-35638. doi: 10.18632/oncotarget.15823. Oncotarget. 2017. PMID: 28404944 Free PMC article.
Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase.
Igarashi K, Li S, Han Q, Tan Y, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: han q. J Cell Biochem. 2018 Apr;119(4):3537-3544. doi: 10.1002/jcb.26527. Epub 2018 Jan 2. J Cell Biochem. 2018. PMID: 29143983
4,818 results