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Mettl3-mediated m6A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Dai G, Huang S, Li Y, Tu X, Xia J, Zhou Z, Chen W, Zhang A, Lin J, Li Y, He D, Lin T, Cong J, Lei Y, Han L, Yao Z, Liu W, Zhou Y, Li Q, Li J, Zhang Y, Wu A, Xiao D, Wang W, Zhao W, Jia J, Lin X. Dai G, et al. Among authors: han l. Aging (Albany NY). 2023 Jun 16;15(12):5550-5568. doi: 10.18632/aging.204810. Epub 2023 Jun 16. Aging (Albany NY). 2023. PMID: 37335109 Free PMC article.
Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways.
Liu Y, Li YQ, Huang SH, Li YL, Xia JW, Jia JS, Wei F, Wang JH, Dai GQ, Wang YC, Li XY, Han LX, Zhang XL, Xiang XD, Zhao WT, Xiao D, Lin XL. Liu Y, et al. Aging (Albany NY). 2021 Sep 13;13(17):21155-21190. doi: 10.18632/aging.203402. Epub 2021 Sep 13. Aging (Albany NY). 2021. PMID: 34517344 Free PMC article.
Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality.
Huang S, Li Y, Wang B, Zhou Z, Li Y, Shen L, Cong J, Han L, Xiang X, Xia J, He D, Zhao Z, Zhou Y, Li Q, Dai G, Shen H, Lin T, Wu A, Jia J, Xiao D, Li J, Zhao W, Lin X. Huang S, et al. Among authors: han l. Aging (Albany NY). 2024 Apr 22;16(8):7217-7248. doi: 10.18632/aging.205753. Epub 2024 Apr 22. Aging (Albany NY). 2024. PMID: 38656880 Free article.
Global One Health index for zoonoses: A performance assessment in 160 countries and territories.
Sun ZS, Wan EY, Agbana YL, Zhao HQ, Yin JX, Jiang TG, Li Q, Fei SW, Wu LB, Li XC, Zhang QY, Liu JS, Gu SY, Guo ZY, Xue JB, Han LF, Zhang XX, Xia S, Welburn SC, Okpeku M, Guo XK, Wang ZJ, Chen JH, Zhang Y, Zhou XN, Kassegne K. Sun ZS, et al. Among authors: han lf. iScience. 2024 Mar 11;27(4):109297. doi: 10.1016/j.isci.2024.109297. eCollection 2024 Apr 19. iScience. 2024. PMID: 38715943 Free PMC article.
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