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A Nonconserved Histidine Residue on KRAS Drives Paralog Selectivity of the KRASG12D Inhibitor MRTX1133.
Cancer Res. 2023 Sep 1;83(17):2816-2823. doi: 10.1158/0008-5472.CAN-23-0592.
Cancer Res. 2023.
PMID: 37339170
Free PMC article.
Development of a novel near-infrared fluorescent theranostic combretastain A-4 analogue, YK-5-252, to target triple negative breast cancer.
Kong Y, Smith J, Li K, Cui J, Han J, Hou S, Brown ML.
Kong Y, et al.
Bioorg Med Chem. 2017 Apr 1;25(7):2226-2233. doi: 10.1016/j.bmc.2017.02.046. Epub 2017 Feb 24.
Bioorg Med Chem. 2017.
PMID: 28284864
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The Nrf1 transcription factor is induced by patulin and protects against patulin cytotoxicity.
Han JJW, Nguyen CD, Thrasher JP, DeGuzman A, Chan JY.
Han JJW, et al.
Toxicology. 2022 Apr 15;471:153173. doi: 10.1016/j.tox.2022.153173. Epub 2022 Mar 31.
Toxicology. 2022.
PMID: 35367319
Free PMC article.
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The deubiquitinating enzyme USP7 regulates the transcription factor Nrf1 by modulating its stability in response to toxic metal exposure.
Han JJW, Ho DV, Kim HM, Lee JY, Jeon YS, Chan JY.
Han JJW, et al.
J Biol Chem. 2021 Jan-Jun;296:100732. doi: 10.1016/j.jbc.2021.100732. Epub 2021 Apr 30.
J Biol Chem. 2021.
PMID: 33933455
Free PMC article.
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