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KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming.
Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, Dai S, Zhang M, Wang Y, Wang B, Zheng J, Wang Y, Xu J, Wang J, Wu B, Chen M, Liu H, Xue J, Huang M, Gong Y, Zhu J, Zhou L, Zhang Y, Yu M, Tian P, Fan M, Lu Z, Xue Z, Zhao Y, Yang H, Zhao C, Wang Y, Han J, Yang S, Xie D, Chen L, Zhong Q, Zeng M, Lowe SW, Lu Y, Liu Y, Wei Y, Chen C. Na F, et al. Among authors: han j. Nat Cancer. 2022 Jun;3(6):753-767. doi: 10.1038/s43018-022-00361-6. Epub 2022 Apr 21. Nat Cancer. 2022. PMID: 35449309 Free PMC article.
From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer.
Zhang CH, Chen K, Jiao Y, Li LL, Li YP, Zhang RJ, Zheng MW, Zhong L, Huang SZ, Song CL, Lin WT, Yang J, Xiang R, Peng B, Han JH, Lu GW, Wei YQ, Yang SY. Zhang CH, et al. Among authors: han jh. J Med Chem. 2016 Nov 10;59(21):9788-9805. doi: 10.1021/acs.jmedchem.6b00943. Epub 2016 Oct 26. J Med Chem. 2016. PMID: 27739679
Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51.
Tao L, Zhou Y, Pan X, Luo Y, Qiu J, Zhou X, Chen Z, Li Y, Xu L, Zhou Y, Zuo Z, Liu C, Wang L, Liu X, Tian X, Su N, Yang Z, Zhang Y, Gou K, Sang N, Liu H, Zou J, Xiao Y, Zhong X, Xu J, Yang X, Xiao K, Liu Y, Yang S, Peng Y, Han J, Cen X, Zhao Y. Tao L, et al. Among authors: han j. Nat Commun. 2023 Nov 16;14(1):7430. doi: 10.1038/s41467-023-42850-x. Nat Commun. 2023. PMID: 37973845 Free PMC article.
Redox regulation of microRNAs in cancer.
Lan J, Huang Z, Han J, Shao J, Huang C. Lan J, et al. Among authors: han j. Cancer Lett. 2018 Apr 1;418:250-259. doi: 10.1016/j.canlet.2018.01.010. Epub 2018 Jan 9. Cancer Lett. 2018. PMID: 29330105 Review.
Histone H3G34 Mutation in Brain and Bone Tumors.
Qiu L, Han J. Qiu L, et al. Among authors: han j. Adv Exp Med Biol. 2021;1283:63-71. doi: 10.1007/978-981-15-8104-5_5. Adv Exp Med Biol. 2021. PMID: 33155138
30,336 results
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