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Ezrin Inhibition Up-regulates Stress Response Gene Expression.
Çelik H, Bulut G, Han J, Graham GT, Minas TZ, Conn EJ, Hong SH, Pauly GT, Hayran M, Li X, Özdemirli M, Ayhan A, Rudek MA, Toretsky JA, Üren A. Çelik H, et al. Among authors: han j. J Biol Chem. 2016 Jun 17;291(25):13257-70. doi: 10.1074/jbc.M116.718189. Epub 2016 May 2. J Biol Chem. 2016. PMID: 27137931 Free PMC article.
YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.
Minas TZ, Han J, Javaheri T, Hong SH, Schlederer M, Saygideğer-Kont Y, Çelik H, Mueller KM, Temel I, Özdemirli M, Kovar H, Erkizan HV, Toretsky J, Kenner L, Moriggl R, Üren A. Minas TZ, et al. Among authors: han j. Oncotarget. 2015 Nov 10;6(35):37678-94. doi: 10.18632/oncotarget.5520. Oncotarget. 2015. PMID: 26462019 Free PMC article.
Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.
Minas TZ, Surdez D, Javaheri T, Tanaka M, Howarth M, Kang HJ, Han J, Han ZY, Sax B, Kream BE, Hong SH, Çelik H, Tirode F, Tuckermann J, Toretsky JA, Kenner L, Kovar H, Lee S, Sweet-Cordero EA, Nakamura T, Moriggl R, Delattre O, Üren A. Minas TZ, et al. Among authors: han j, han zy. Oncotarget. 2017 May 23;8(21):34141-34163. doi: 10.18632/oncotarget.9388. Oncotarget. 2017. PMID: 27191748 Free PMC article.
Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99.
Çelik H, Sciandra M, Flashner B, Gelmez E, Kayraklıoğlu N, Allegakoen DV, Petro JR, Conn EJ, Hour S, Han J, Oktay L, Tiwari PB, Hayran M, Harris BT, Manara MC, Toretsky JA, Scotlandi K, Üren A. Çelik H, et al. Among authors: han j. Oncogene. 2018 Apr;37(16):2181-2196. doi: 10.1038/s41388-017-0080-4. Epub 2018 Jan 31. Oncogene. 2018. PMID: 29382926 Free PMC article.
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