Han HW - Search Results

1

The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosis.

Han HW, Zheng CS, Chu SJ, Sun WX, Han LJ, Yang RW, Qi JL, Lu GH, Wang XM, Yang YH. Han HW, et al. Among authors: han lj. Biomed Pharmacother. 2018 Jan;97:656-666. doi: 10.1016/j.biopha.2017.10.159. Epub 2017 Nov 6. Biomed Pharmacother. 2018. PMID: 29101810

2

Novel shikonin derivatives targeting tubulin as anticancer agents.

Guo J, Chen XF, Liu J, Lin HY, Han HW, Liu HC, Huang SC, Shahla BK, Kulek A, Qi JL, Wang XM, Ling LJ, Yang YH. Guo J, et al. Among authors: han hw. Chem Biol Drug Des. 2014 Nov;84(5):603-15. doi: 10.1111/cbdd.12353. Epub 2014 Jul 3. Chem Biol Drug Des. 2014. PMID: 24797889

3

Design, synthesis and anti-cancer activity evaluation of podophyllotoxin-norcantharidin hybrid drugs.

Han HW, Qiu HY, Hu C, Sun WX, Yang RW, Qi JL, Wang XM, Lu GH, Yang YH. Han HW, et al. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3237-3242. doi: 10.1016/j.bmcl.2016.05.063. Epub 2016 May 24. Bioorg Med Chem Lett. 2016. PMID: 27262599

4

Antiviral activity of a synthesized shikonin ester against influenza A (H1N1) virus and insights into its mechanism.

Zhang Y, Han H, Qiu H, Lin H, Yu L, Zhu W, Qi J, Yang R, Pang Y, Wang X, Lu G, Yang Y. Zhang Y, et al. Biomed Pharmacother. 2017 Sep;93:636-645. doi: 10.1016/j.biopha.2017.06.076. Epub 2017 Jul 5. Biomed Pharmacother. 2017. PMID: 28688289

5

Design and synthesis of piperazine acetate podophyllotoxin ester derivatives targeting tubulin depolymerization as new anticancer agents.

Sun WX, Ji YJ, Wan Y, Han HW, Lin HY, Lu GH, Qi JL, Wang XM, Yang YH. Sun WX, et al. Among authors: han hw. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4066-4074. doi: 10.1016/j.bmcl.2017.07.047. Epub 2017 Jul 20. Bioorg Med Chem Lett. 2017. PMID: 28757065

6

Antiviral activity of shikonin ester derivative PMM-034 against enterovirus 71 in vitro.

Zhang Y, Han H, Sun L, Qiu H, Lin H, Yu L, Zhu W, Qi J, Yang R, Pang Y, Wang X, Lu G, Yang Y. Zhang Y, et al. Braz J Med Biol Res. 2017 Aug 17;50(10):e6586. doi: 10.1590/1414-431X20176586. Braz J Med Biol Res. 2017. PMID: 28832767 Free PMC article.

7

Identification of new shikonin derivatives as STAT3 inhibitors.

Qiu HY, Fu JY, Yang MK, Han HW, Wang PF, Zhang YH, Lin HY, Tang CY, Qi JL, Yang RW, Wang XM, Zhu HL, Yang YH. Qiu HY, et al. Among authors: han hw. Biochem Pharmacol. 2017 Dec 15;146:74-86. doi: 10.1016/j.bcp.2017.10.009. Epub 2017 Oct 21. Biochem Pharmacol. 2017. PMID: 29066190

8

Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.

Lin HY, Han HW, Sun WX, Yang YS, Tang CY, Lu GH, Qi JL, Wang XM, Yang YH. Lin HY, et al. Among authors: han hw. Eur J Med Chem. 2018 Jan 20;144:137-150. doi: 10.1016/j.ejmech.2017.12.019. Epub 2017 Dec 7. Eur J Med Chem. 2018. PMID: 29268130

9

Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.

Han HW, Lin HY, He DL, Ren Y, Sun WX, Liang L, Du MH, Li DC, Chu YC, Yang MK, Wang XM, Yang YH. Han HW, et al. Chem Biodivers. 2018 Nov;15(11):e1800289. doi: 10.1002/cbdv.201800289. Epub 2018 Oct 31. Chem Biodivers. 2018. PMID: 30194898

10

Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.

Sun WX, Han HW, Yang MK, Wen ZL, Wang YS, Fu JY, Lu YT, Wang MY, Bao JX, Lu GH, Qi JL, Wang XM, Lin HY, Yang YH. Sun WX, et al. Among authors: han hw. Bioorg Med Chem. 2019 Dec 1;27(23):115153. doi: 10.1016/j.bmc.2019.115153. Epub 2019 Oct 15. Bioorg Med Chem. 2019. PMID: 31648877

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