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Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules.
Hamulakova S, Poprac P, Jomova K, Brezova V, Lauro P, Drostinova L, Jun D, Sepsova V, Hrabinova M, Soukup O, Kristian P, Gazova Z, Bednarikova Z, Kuca K, Valko M. Hamulakova S, et al. J Inorg Biochem. 2016 Aug;161:52-62. doi: 10.1016/j.jinorgbio.2016.05.001. Epub 2016 May 5. J Inorg Biochem. 2016. PMID: 27230386
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
Janockova J, Korabecny J, Plsikova J, Babkova K, Konkolova E, Kucerova D, Vargova J, Koval J, Jendzelovsky R, Fedorocko P, Kasparkova J, Brabec V, Rosocha J, Soukup O, Hamulakova S, Kuca K, Kozurkova M. Janockova J, et al. Among authors: hamulakova s. J Enzyme Inhib Med Chem. 2019 Dec;34(1):877-897. doi: 10.1080/14756366.2019.1593159. J Enzyme Inhib Med Chem. 2019. PMID: 30938202 Free PMC article.
Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.
Hamulakova S, Kudlickova Z, Janovec L, Mezencev R, Deckner ZJ, Chernoff YO, Janockova J, Ihnatova V, Bzonek P, Novakova N, Hepnarova V, Hrabinova M, Jun D, Korabecny J, Soukup O, Kuca K. Hamulakova S, et al. Future Med Chem. 2021 May;13(9):785-804. doi: 10.4155/fmc-2020-0184. Epub 2021 Apr 8. Future Med Chem. 2021. PMID: 33829876 Free PMC article.
Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.
Janočková J, Plšíková J, Koval' J, Jendželovský R, Mikeš J, Kašpárková J, Brabec V, Hamuľaková S, Fedoročko P, Kožurková M. Janočková J, et al. Among authors: hamulakova s. Bioorg Chem. 2015 Apr;59:168-76. doi: 10.1016/j.bioorg.2015.03.002. Epub 2015 Mar 19. Bioorg Chem. 2015. PMID: 25827869
17 results