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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ. Runtsch MC, et al. Among authors: hams e. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002. Cell Metab. 2022. PMID: 35235776 Free article.
Innate type 2 cells and asthma.
Hams E, Fallon PG. Hams E, et al. Curr Opin Pharmacol. 2012 Aug;12(4):503-9. doi: 10.1016/j.coph.2012.06.001. Epub 2012 Jun 29. Curr Opin Pharmacol. 2012. PMID: 22749407 Review.
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.
Spence S, Fitzsimons A, Boyd CR, Kessler J, Fitzgerald D, Elliott J, Gabhann JN, Smith S, Sica A, Hams E, Saunders SP, Jefferies CA, Fallon PG, McAuley DF, Kissenpfennig A, Johnston JA. Spence S, et al. Among authors: hams e. Immunity. 2013 Jan 24;38(1):66-78. doi: 10.1016/j.immuni.2012.09.013. Epub 2012 Nov 21. Immunity. 2013. PMID: 23177319 Free article. Retracted.
The schistosoma granuloma: friend or foe?
Hams E, Aviello G, Fallon PG. Hams E, et al. Front Immunol. 2013 Apr 15;4:89. doi: 10.3389/fimmu.2013.00089. eCollection 2013. Front Immunol. 2013. PMID: 23596444 Free PMC article.
46 results