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Secukinumab in plaque psoriasis--results of two phase 3 trials.
N Engl J Med. 2014 Jul 24;371(4):326-38. doi: 10.1056/NEJMoa1314258. Epub 2014 Jul 9.
N Engl J Med. 2014.
PMID: 25007392
Free article.
Clinical Trial.
Efficacy, tolerability, patient usability, and satisfaction with a 2 mL pre-filled syringe containing secukinumab 300 mg in patients with moderate to severe plaque psoriasis: results from the phase 3 randomized, double-blind, placebo-controlled ALLURE study.
Sigurgeirsson B, Schäkel K, Hong CH, Effendy I, Placek W, Rich P, Keefe D, Bruin G, Charef P, Fu R, Hampele I, Patekar M.
Sigurgeirsson B, et al. Among authors: hampele i.
J Dermatolog Treat. 2022 May;33(3):1718-1726. doi: 10.1080/09546634.2021.1902925. Epub 2021 Apr 26.
J Dermatolog Treat. 2022.
PMID: 33896356
Clinical Trial.
Item in Clipboard
Secukinumab demonstrates efficacy, safety, and tolerability upon administration by 2 ml autoinjector in adult patients with plaque psoriasis: 52-week results from MATURE, a randomized, placebo-controlled trial.
Sigurgeirsson B, Browning J, Tyring S, Szepietowski JC, Rivera-Díaz R, Effendy I, Keefe D, Bruin G, Paguet B, Fu R, Hampele I, Reinhardt M, Patekar M.
Sigurgeirsson B, et al. Among authors: hampele i.
Dermatol Ther. 2022 Mar;35(3):e15285. doi: 10.1111/dth.15285. Epub 2022 Jan 8.
Dermatol Ther. 2022.
PMID: 34954841
Clinical Trial.
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Secukinumab long-term efficacy and safety in psoriasis through to year 5 of treatment: results of a randomized extension of the phase III ERASURE and FIXTURE trials.
Langley RG, Sofen H, Dei-Cas I, Reich K, Sigurgeirsson B, Warren RB, Paul C, Szepietowski JC, Tsai TF, Hampele I, You R, Charef P, Papavassilis C.
Langley RG, et al. Among authors: hampele i.
Br J Dermatol. 2023 Feb 10;188(2):198-207. doi: 10.1093/bjd/ljac040.
Br J Dermatol. 2023.
PMID: 36763857
Clinical Trial.
Item in Clipboard
Secukinumab in adult patients with lichen planus: Efficacy and safety results from the randomised, placebo-controlled, proof-of-concept PRELUDE study.
Passeron T, Reinhardt M, Ehst B, Weiss J, Sluzevich J, Sticherling M, Reygagne P, Wohlrab J, Hertl M, Fazel N, Muscianisi E, Fan H, Hampele I, Compagno N.
Passeron T, et al. Among authors: hampele i.
Br J Dermatol. 2024 May 13:ljae181. doi: 10.1093/bjd/ljae181. Online ahead of print.
Br J Dermatol. 2024.
PMID: 38735684
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Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus.
Hennig M, D'Arcy A, Hampele IC, Page MG, Oefner C, Dale GE.
Hennig M, et al. Among authors: hampele ic.
Nat Struct Biol. 1998 May;5(5):357-62. doi: 10.1038/nsb0598-357.
Nat Struct Biol. 1998.
PMID: 9586996
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Structure and function of the dihydropteroate synthase from Staphylococcus aureus.
Hampele IC, D'Arcy A, Dale GE, Kostrewa D, Nielsen J, Oefner C, Page MG, Schönfeld HJ, Stüber D, Then RL.
Hampele IC, et al.
J Mol Biol. 1997 Apr 25;268(1):21-30. doi: 10.1006/jmbi.1997.0944.
J Mol Biol. 1997.
PMID: 9149138
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